Characterization, antimicrobial, antioxidant, and anticoagulant activities of silver nanoparticles synthesized from L. leaf extract.

Phytosynthesis of silver nanoparticles (AgNPs) using leaf extract of () was the focus of this research work. The -AgNPs were characterized by UV-Vis spectroscopy, Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and selected area electron diffraction (SAED) study. Studies were made on the AgNPs for antibacterial, antifungal, anticoagulant, free-radical scavenging, and hydrogen peroxide scavenging activities. The crystalline -AgNPs were monodispersed, with a size range of 16.70-33.74 nm and maximum absorption at 410 nm. FTIR analysis displayed prominent peaks at 3430.6, 1711.8, and 1165.9/cm, which showed the existence of phenolic compounds and proteins in the synthesis of AgNPs. -AgNPs was active against , , and , with 100% inhibition. The -AgNPs also displayed good antifungal properties, as the concentrations of 100 and 150 µg/mL had 100% inhibition toward and . However, there was 66.67% inhibition of . It scavenged both DPPH and HO by 70.69 and 89.02%, respectively. -AgNPs also prevented the coagulation of human blood. This study, being the first of its kind to use the leaf extract of for the synthesis of AgNPs has shown that -AgNPs can find biomedical applications.