Sarfehnia Arman, Ruschin Mark, Chugh Brige, Yeboah Collins, Becker Nathan, Cho Young-Bin, Lee Young
Department of Radiation Oncology, University of Toronto, 150 College St., Toronto, ON, M5S-3E2, Canada.
Department of Medical Physics, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave., Toronto, ON, M4N-3M5, Canada.
Med Phys. 2018 Jun 29. doi: 10.1002/mp.13073.
This work describes the performance characterization of a cone-beam CT-guided radiosurgery device, the Gamma Knife Icon™.
The performance tests have been categorized into: (a) image quality and mechanical integrity; (b) image coregistration fidelity; (c) adaptive treatment delivery quality; (d) high definition motion management performance characterization; (e) software communication performance testing of the integrated cone-beam CT (CBCT) system.
All image quality performance characterization satisfied or exceeded manufacturer specifications. The image quality and mechanical stability of the CBCT system over a 3-month period was within tolerance with negligible (<0.1°) detector tilt angle. The CBCT definition of the stereotactic space had a measured average discrepancy of 0.15-0.16 mm in x, y, and z directions. On average, the high definition motion management system performance was within 0.05 mm with a residual offset of 0.15 mm when large displacements in a given direction were taken. The adaptive treatment delivery component as measured with CBCT coregistration of daily setups against reference setup images was accurate to within 0.2°. Comprehensive end-to-end testing showed a total uncertainty of better than 0.2 mm in positioning and 0.4% in dosimetry for treatment of centrally located lesions.
A set of system performance characterization tests spanning all aspects of the Gamma Knife Icon are presented. Overall, the system performance was in line with manufacturer specifications.
本研究描述了一种锥束CT引导的放射外科设备——伽玛刀Icon™的性能特征。
性能测试分为以下几类：（a）图像质量和机械完整性；（b）图像配准保真度；（c）自适应治疗输送质量；（d）高清运动管理性能特征；（e）集成锥束CT（CBCT）系统的软件通信性能测试。
所有图像质量性能特征均满足或超过制造商规格。CBCT系统在3个月期间的图像质量和机械稳定性在公差范围内，探测器倾斜角度可忽略不计（<0.1°）。立体定向空间的CBCT定义在x、y和z方向上的测量平均偏差为0.15 - 0.16毫米。平均而言，高清运动管理系统性能在给定方向上进行大位移时，偏差在0.05毫米以内，残余偏移为0.15毫米。通过将每日设置的CBCT与参考设置图像进行配准来测量的自适应治疗输送组件，其精度在0.2°以内。全面的端到端测试表明，对于中心位置病变的治疗，定位总不确定度优于0.2毫米，剂量测定总不确定度优于0.4%。
本文展示了一组涵盖伽玛刀Icon各个方面的系统性能特征测试。总体而言，系统性能符合制造商规格。
