Dougherty Danielle, Onyemkpa Chibueze, Engel Michael, Oyasiji Tolutope
Michigan State University, Department of Surgery, 1200 East Michigan Ave., Suite 655, Lansing, MI 48912, United States.
Michigan State University, Department of Surgery, 1200 East Michigan Ave., Suite 655, Lansing, MI 48912, United States.
Int J Surg Case Rep. 2018;49:40-43. doi: 10.1016/j.ijscr.2018.05.007. Epub 2018 May 26.
Brenner Tumors are rare adenofibromas that are most commonly benign and discovered in post-menopausal women.
This is a case report of a 57-year-old female with three months of progressively worsening abdominal pain due to a large abdominal mass discovered on CT scan. Surgical removal of the mass revealed a giant mucinous tumor of the ovary with an associated Brenner tumor that was discovered incidentally.
Although the Brenner tumor was accurately identified in the intraoperative frozen section evaluation, the mucinous tumor was underdiagnosed by frozen section as benign when permanent section revealed borderline mucinous cystadenoma. This finding did not change the treatment course for this particular patient as she had expressed personal preference for total abdominal hysterectomy. However, underdiagnosis of frozen sections of ovarian tumors is not rare. It is unclear whether an associated Brenner tumor increases malignancy potential.
Further investigation is required to determine whether associated Brenner tumors found during frozen section are more highly associated with malignancy and could therefore change intraoperative and overall decision making.
勃勒纳瘤是一种罕见的腺纤维瘤，最常见于绝经后女性，通常为良性。
本文报告一例57岁女性，因CT扫描发现腹部巨大肿块，出现进行性加重的腹痛3个月。手术切除肿块后发现为卵巢巨大黏液性肿瘤，同时意外发现合并勃勒纳瘤。
尽管在术中冰冻切片评估中准确识别出了勃勒纳瘤，但黏液性肿瘤在冰冻切片时被误诊为良性，而永久切片显示为交界性黏液性囊腺瘤。这一发现并未改变该特定患者的治疗方案，因为她个人倾向于行全腹子宫切除术。然而，卵巢肿瘤冰冻切片诊断不足并不罕见。尚不清楚合并的勃勒纳瘤是否会增加恶性潜能。
需要进一步研究以确定在冰冻切片中发现的合并勃勒纳瘤是否与恶性肿瘤更高度相关，从而改变术中及总体决策。
