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与入住养老院患者 6 个月生存率相关的预后模型。

Prognostic Models Associated with 6-Month Survival of Patients Admitted to Nursing Homes.

机构信息

University of Granada, Granada, Spain.

University of Jaén, Jaén,

出版信息

Gerontology. 2019;65(1):40-44. doi: 10.1159/000490243. Epub 2018 Jun 29.

Abstract

BACKGROUND

Health status and the needs presented by people admitted to nursing homes make it necessary to contemplate aspects such as prognosis to offer quality palliative care.

OBJECTIVE

To compare the prognostic utility in nursing homes of two prognostic models of 6-month survival based on the Palliative Prognostic Index (PPI) or Palliative Performance Status (PPS) instruments and palliative needs indicators.

METHODS

A longitudinal prospective observational and analytical cohort study of survival and prognostic models in 88 patients with palliative needs (assessed by the NECPAL-ICO-CCOMS©) from an Andalusian (Spain) nursing home was performed. Sociodemographic and clinical variables were assessed, and 6 months later, in September 2017, survival was checked. Multiple logistic regression analysis was performed using the R-Commander program (version 3.2.2).

RESULTS

Two models of the logistic regression analysis met the fit criteria. The two models combined the Surprise Question, the presence of persistent symptoms, and the clinical indicators of severity from the NECPAL tool, in addition to the Charlson Comorbidity Index, and varied only in terms of the latter variable, including the PPI in the first model and the PPS in the second. In the first model, significant associations were identified between 6-month survival and the persistent symptoms variable (OR = 7.78, p = 0.025, 95% CI = 1.45-60.92) and PPI (OR = 1.94, p < 0.001, 95% CI = 1.21). In the second model, 6-month survival was also significantly associated with the persistent symptoms variable (OR = 4.57, p = 0.045, 95% CI = 1.07-22.41) and the PPS (OR = 0.93, p = 0.001, 95% CI = 0.88-0.96).

CONCLUSIONS

Prognostic models such as ours that include variables commonly included in clinical assessments can help nursing home professionals prioritize and ensure adequate mobilization of palliative care resources, which are very limited in these institutions.

摘要

背景

入住养老院的患者的健康状况和需求使得有必要考虑预后等方面,以提供优质的姑息治疗。

目的

比较两种基于姑息预后指数(PPI)或姑息表现状态(PPS)工具和姑息需求指标的 6 个月生存率预后模型在养老院中的预后预测价值。

方法

对来自西班牙安达卢西亚一家养老院(n=88)的姑息需求患者(通过 NECPAL-ICO-CCOMS© 评估)进行了一项前瞻性纵向观察性分析队列研究,评估了患者的社会人口统计学和临床变量,并于 2017 年 9 月(即 6 个月后)检查了患者的生存情况。使用 R-Commander 程序(版本 3.2.2)进行了多项逻辑回归分析。

结果

两种逻辑回归分析模型均符合拟合标准。这两种模型均结合了意外问题、持续症状以及 NECPAL 工具中的严重程度临床指标,除了 Charlson 合并症指数外,还包括 PPI(模型 1)和 PPS(模型 2)。在模型 1 中,6 个月生存率与持续症状变量(OR=7.78,p=0.025,95%CI=1.45-60.92)和 PPI(OR=1.94,p<0.001,95%CI=1.21)显著相关。在模型 2 中,6 个月生存率也与持续症状变量(OR=4.57,p=0.045,95%CI=1.07-22.41)和 PPS(OR=0.93,p=0.001,95%CI=0.88-0.96)显著相关。

结论

像我们这样的预后模型包括了通常包含在临床评估中的变量,可以帮助养老院的专业人员优先考虑和确保姑息治疗资源的充分调动,因为这些资源在这些机构中非常有限。

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