van der Merwe Johan, Casselman Filip, Van Praet Frank
Department of Cardiovascular and Thoracic Surgery, Onze Lieve Vrouw Clinic, Aalst, Belgium.
J Vis Surg. 2018 May 11;4:100. doi: 10.21037/jovs.2018.05.01. eCollection 2018.
The continuous evolution in robotic-, endoscopic- and trans-catheter cardiac interventions resulted in innovative techniques that simultaneously address left ventricular outflow tract obstruction (LVOTO) and concomitant atrioventricular valve (AVV) pathology in the context of hypertrophic obstructive cardiomyopathy (HOCM). We present our brief report of 13 consecutive HOCM patients with concomitant AVV disease, who underwent endoscopic left ventricular septal myomectomy (LVSM) and AVV surgery by Endoscopic Port Access Surgery (EPAS) between March 1st 2010 and October 31st 2015. Our EPAS technique in the context of HOCM utilizes peripheral cardiopulmonary bypass, endo-aortic balloon occlusion and a 4-cm right antero-lateral thoracic working port. Access to the LVOTO is obtained by detaching the anterior mitral valve (MV) leaflet from the annulus. Controlled sharp LVSM is then performed from the aortic leaflet base to the papillary muscles. Subsequent routine AVV surgery is performed using long shafted instruments. There were no sternotomy conversions, LVSM complications or 30-day mortalities. The mean length of hospitalization was 17.7±18.1 days. Long-term clinical and echocardiographic analysis of 645.7 patient-months (n=13, 100.0% complete) identified two late mortalities, which were not procedure-, HOCM- or AVV-related. All patients (n=13, 100.0%), including the late mortalities, had significant improvement in their quality of life, a 100% long-term freedom from re-intervention and no residual peak instantaneous LVOTO gradients more than 15 mmHg. This brief report emphasises that simultaneous LVSM and concomitant AVV surgery by EPAS can safely be performed in experienced centres with favourable long-term outcomes.
机器人辅助、内镜及经导管心脏介入技术的不断发展催生了创新技术,这些技术可在肥厚性梗阻性心肌病(HOCM)的背景下,同时解决左心室流出道梗阻(LVOTO)及伴发的房室瓣(AVV)病变问题。我们简要报告了13例连续的伴有AVV疾病的HOCM患者,他们于2010年3月1日至2015年10月31日期间接受了内镜下左心室间隔心肌切除术(LVSM)及经内镜端口入路手术(EPAS)进行的AVV手术。我们在HOCM背景下的EPAS技术采用外周体外循环、主动脉内球囊阻断及一个4厘米的右侧前外侧胸壁工作端口。通过将二尖瓣(MV)前叶与瓣环分离来进入LVOTO。然后从主动脉瓣叶基部至乳头肌进行可控的锐性LVSM。随后使用长柄器械进行常规AVV手术。没有转为开胸手术的情况,没有LVSM并发症,也没有30天死亡率。平均住院时间为17.7±18.1天。对645.7患者月(n = 13,100.0%完整)的长期临床及超声心动图分析发现了两例晚期死亡病例,这两例与手术、HOCM或AVV无关。所有患者(n = 13,100.0%),包括晚期死亡患者,生活质量均有显著改善,长期免于再次干预的比例为100%,且没有残留的瞬时LVOTO峰值梯度超过15 mmHg。本简要报告强调,在有经验的中心,通过EPAS同时进行LVSM及伴发的AVV手术可安全实施,且长期效果良好。