Karande Vikram, Andrade Neelam N
Department of Oral and Maxillofacial Surgery, Terna Dental College, Nerul, India.
Department of Oral and Maxillofacial Surgery, Nair Hospital Dental College, Mumbai, Maharashtra, India.
Ann Maxillofac Surg. 2018 Jan-Jun;8(1):131-136. doi: 10.4103/ams.ams_34_16.
It has been very aptly quoted, "Variety is the spice of life"; and so variations exist in all forms and kinds good or bad, and for the worst or the best! Mother nature in all her glory and beauty has been very generous, but what when she fails to provide? It is this very character of nature that gives us variations which sometimes manifest in a cruel way on the human body and gives us the eponym of syndromes. Dandy-Walker malformation is an abnormality of the central nervous system, which leads to hydrocephalus and is associated with other abnormalities. Neurologic symptoms are the norm in afflicted patients due to the inherent nature of the disease in that it affects the very center of human function-the brain. This article brings to you a very unique, challenging and rare case of a young patient with this debilitating disorder who was also affected with giant cell lesions of the maxilla and mandible along with cherubism. It highlights the unpredictable course and progression of the disease in a child and our unique protocol employed for the management of the same. It adds providence and a new perspective to the still ambiguous nature of this disorder and the unprecedented maxillofacial anomalies, i.e., giant cell lesions and Cherubism associated with the same.
“多样性是生活的调味品”；因此，各种形式和种类的变化都存在，有好有坏，有最坏的，也有最好的！大自然母亲以她所有的荣耀和美丽一直都非常慷慨，但当她未能提供时会怎样呢？正是大自然的这种特性给了我们各种变化，这些变化有时会以一种残酷的方式在人体上表现出来，并给我们带来了各种综合征的名称。丹迪-沃克畸形是一种中枢神经系统异常，会导致脑积水，并与其他异常情况相关联。由于这种疾病的内在性质，即它影响人类功能的核心——大脑，神经系统症状在患病患者中很常见。本文为您带来一个非常独特、具有挑战性且罕见的病例，一名患有这种使人衰弱疾病的年轻患者，同时还患有上颌骨和下颌骨的巨细胞病变以及颌骨多囊病。它突出了该疾病在儿童中不可预测的病程和进展，以及我们用于治疗该疾病的独特方案。它为这种仍然模糊不清的疾病性质以及前所未有的颌面异常情况，即与之相关的巨细胞病变和颌骨多囊病，增添了天意和新的视角。
