Beghi E, Kurland L T, Mulder D W, Nicolosi A
Ann Neurol. 1985 Sep;18(3):320-3. doi: 10.1002/ana.410180308.
Brachial plexus neuropathy (BPN) is a clinical entity of unknown cause characterized by the acute or subacute onset of pain and weakness, with occasional atrophy of the arm muscles. Information on the incidence of the disease in a delineated population is lacking, as the data available on BPN have come essentially from case reports or selected series. Using the Mayo Clinic records-linkage system as the source of data, 579 clinical records were reviewed of Rochester, Minnesota, residents in which a diagnosis suggestive of BPN was reported for the period 1970 through 1981. Eleven cases fulfilled all criteria, providing an overall annual incidence rate of 1.64 cases per 100,000 population. An infectious disease and/or tetanus toxoid immunization preceded the onset of BPN in 4 cases. The upper brachial plexus was involved in 6 cases, the lower brachial plexus in 2, and the whole plexus in 3; in 1 case there was bilateral BPN. The neuropathy ran a mild to moderate course in 10 cases, and complete recovery was recorded in 6, with slight residua in the others. The occurrence of antecedent events and the features of the disease are supportive of the concept of an immune-mediated process.
臂丛神经病（BPN）是一种病因不明的临床病症，其特征为疼痛和无力急性或亚急性发作，偶尔伴有手臂肌肉萎缩。由于关于BPN的数据基本上来自病例报告或选定的系列研究，因此缺乏关于特定人群中该疾病发病率的信息。以梅奥诊所记录链接系统作为数据来源，对明尼苏达州罗切斯特市1970年至1981年期间报告有疑似BPN诊断的579份临床记录进行了审查。11例符合所有标准，总体年发病率为每10万人1.64例。4例BPN发病前有传染病和/或破伤风类毒素免疫接种史。6例累及臂丛神经上部，2例累及下部，3例累及整个臂丛神经；1例为双侧BPN。10例患者的神经病变呈轻度至中度病程，6例完全恢复，其他患者有轻微后遗症。前驱事件的发生和疾病特征支持免疫介导过程的概念。
