Kekule-Institut für Organische Chemie und Biochemie, Rheinische Friedrich-Wilhelms-Universität Bonn, Gerhard-Domagk-Str. 1, 53121, Bonn, Germany.
Chemistry. 2018 Aug 14;24(46):12006-12009. doi: 10.1002/chem.201802567. Epub 2018 Jul 18.
In a convergent, template-directed synthesis, an efficient route to a phenylene-ethynylene-butadiynylene based [2]catenane is described. The key step is performed by the aminolysis of the corresponding precatenane, which is obtained by a sequence of metal-catalyzed cross-coupling and desilylation reactions. The cyclization reaction leads besides the [2]precatenane to a variety of larger precatenanes and offers an attractive approach to mechanically interlocked structures of different size.
在一个收敛的、模板导向的合成中，描述了一种有效制备基于苯撑乙炔-丁二炔的[2]轮烷的方法。关键步骤是通过相应的预轮烷的氨解来完成的，该预轮烷是通过一系列金属催化的交叉偶联和脱硅反应得到的。该环化反应除了生成[2]预轮烷外，还生成了各种更大的预轮烷，为不同大小的机械互锁结构提供了一种有吸引力的方法。
