Yin Nai-Yi, Du Hui-Li, Zhang Zhen-Nan, Cai Xiao-Lin, Li Ze-Jiao, Sun Guo-Xin, Cui Yan-Shan
College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China.
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Huan Jing Ke Xue. 2016 Jun 8;37(6):2353-2358. doi: 10.13227/j.hjkx.2016.06.045.
The influence of human gut micobiota on bioaccessibilities of soil Cd, Cr, and Ni were investigated in this study. Five soil samples were collected from some sites of China, and the bioaccessibilities of soil Cd, Cr, and Ni in the gastric, small intestinal, and colon phases were determined using the PBET method (physiologically based extraction test) combined with SHIME model (simulator of human intestinal microbial ecosystem). The results showed that the bioaccessibilities of Cd, Cr, and Ni in the gastric phase were 4.3%-94.0%, 6.4%-21.6%, and 11.3%-47.3%, respectively. In the small intestinal phase, the bioaccessibilities of Cr and Ni were either congruent or slightly increased, while for Cd, the values were reduced by 1.4-1.6 folds except for soil 2. In the gastric and small intestinal phases, the mean bioaccessibility of Cd was higher but that of Cr was lower. In the colon phase, the bioaccessibilities of Cr and Ni were 1.3-2.4 and 1.0-2.1 times higher than those in the small intestinal phase. Furthermore, the bioaccessibility of Cd also increased except for soil 3 and 4. Human gut micobiota could induce Cd, Cr, and Ni release from soils and increase their bioaccessibilities, which may result in high risk to human health.
本研究调查了人体肠道微生物群对土壤中镉、铬和镍生物可及性的影响。从中国的一些地点采集了五个土壤样本，并采用基于生理学的提取试验（PBET）结合人体肠道微生物生态系统模拟器（SHIME）模型，测定了土壤中镉、铬和镍在胃、小肠和结肠阶段的生物可及性。结果表明，镉、铬和镍在胃阶段的生物可及性分别为4.3%-94.0%、6.4%-21.6%和11.3%-47.3%。在小肠阶段，铬和镍的生物可及性要么保持一致，要么略有增加，而对于镉，除土壤2外，其值降低了1.4-1.6倍。在胃和小肠阶段，镉的平均生物可及性较高，而铬的平均生物可及性较低。在结肠阶段，铬和镍的生物可及性分别比小肠阶段高1.3-2.4倍和1.0-2.1倍。此外，除土壤3和4外，镉的生物可及性也有所增加。人体肠道微生物群可诱导土壤中镉、铬和镍的释放并增加其生物可及性，这可能对人体健康造成高风险。
