溴脱氧尿苷对中国仓鼠 - 鸡红细胞体细胞杂种中鸡特异性次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶基因分离的影响。
The effect of bromodeoxyuridine on the segregation of the chicken-specific HPRT gene from Chinese hamster-chick red blood cell somatic hybrids.
作者信息
Raskó I, Péter S L, Dallmann L, Bajszár G, Péter S, Burg K
机构信息
Biological Research Center, Hungarian Academy of Sciences, Szeged.
出版信息
Exp Cell Res. 1978 May;113(2):339-43. doi: 10.1016/0014-4827(78)90374-9.
PMID:299650
Abstract
The segregation of the chick-specific HPRT gene was studied in three Chinese hamster-chick red blood cell hybrid lines. The three lines showed individual segregation kinetics, the segregation taking place in an exponential-like fashion. Bromodeoxyuridine becomes incorporated into the nuclear DNA and increases the spontaneous segregation rate.
摘要
在三个中国仓鼠 - 鸡红细胞杂交系中研究了鸡特异性次黄嘌呤 - 鸟嘌呤磷酸核糖转移酶（HPRT）基因的分离情况。这三个杂交系呈现出各自独特的分离动力学，分离以类似指数的方式发生。溴脱氧尿苷会掺入核DNA中并增加自发分离率。
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