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电灼术与仅使用手术刀的手术相比,并未减少初次全膝关节置换术的失血量:一项双盲随机对照试验。

Electric cautery does not reduce blood loss in primary total knee arthroplasty compared with scalpel only surgery a double-blinded randomized controlled trial.

机构信息

Department of Orthopaedics, Faculty of Medicine, Thammasat University, 99 Moo 18, Khlong Nueng, Khlong Luang, Pathumthani, 12120, Thailand.

出版信息

Int Orthop. 2018 Dec;42(12):2755-2760. doi: 10.1007/s00264-018-4048-y. Epub 2018 Jul 3.

Abstract

PURPOSE

The purpose of this study was to systematically compare blood loss between the electric cautery and scalpel used in primary total knee arthroplasty (TKA).

METHODS

We performed a double-blind trial randomizing osteoarthritic knee patients undergoing unilateral TKA done by either using scalpel (group S) or cautery (group C). Primary outcomes were total blood loss calculated from maximum haemoglobin drop and blood loss collected in drain. Secondary outcomes were systemic inflammatory response (serum C-reactive protein), wound complications, and functional outcomes assessed over three months.

RESULTS

A total of 80 patients were recruited. Group S had similar calculated total blood loss compared to group C (1070 (S) vs 1128 (C) mL, 95% CI - 219 to 103, p = 0.47). There was no difference in the mean drain-collected blood loss between the two groups (443 (S) vs 486 (C) mL, 95% CI - 128 to 47, p = 0.36). Group C had higher serum C-reactive protein level at 48 hours after TKA compare to group S (105 vs 140 mg/dL, 95% CI - 66 to - 4, p = 0.03). Wound complications and functional outcomes at three months were also similar between the two groups.

CONCLUSIONS

Using electric cautery does not reduce total blood loss as we thought it would be in primary TKA compare to scalpel only surgery and it is also associated with a greater systemic inflammatory response. Cautery used in TKA which operated under tourniquet may not be worthwhile for the risk of hazardous smoke and the increasing cost.

摘要

目的

本研究旨在系统比较电动电烙术与手术刀在初次全膝关节置换术(TKA)中的失血量。

方法

我们进行了一项双盲试验,将接受单侧 TKA 的骨关节炎膝关节患者随机分为使用手术刀(S 组)或电烙术(C 组)。主要结局是从最大血红蛋白下降和引流中收集的血液计算总失血量。次要结局是在三个月内评估全身炎症反应(血清 C 反应蛋白)、伤口并发症和功能结局。

结果

共招募了 80 名患者。S 组的计算总失血量与 C 组相似(1070(S)vs 1128(C)mL,95%CI-219 至 103,p=0.47)。两组引流收集的平均失血量无差异(443(S)vs 486(C)mL,95%CI-128 至 47,p=0.36)。与 S 组相比,C 组在 TKA 后 48 小时的血清 C 反应蛋白水平更高(105 与 140mg/dL,95%CI-66 至-4,p=0.03)。两组在三个月时的伤口并发症和功能结局也相似。

结论

与仅使用手术刀的手术相比,电动电烙术在初次 TKA 中并没有像我们想象的那样减少总失血量,而且还与更大的全身炎症反应有关。在止血带下进行 TKA 中使用电烙术可能并不值得,因为存在危险烟雾和增加成本的风险。

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