Jatuworapruk Kanon, Lertnawapan Ratchaya, Ratanabunjerdkul Hataiwan, Kintarak Jutatip, Satdhabudha Opas
Division of Rheumatology, Thammasat University, Pathum Thani, Thailand.
Medical Oncology Unit, Department of Internal Medicine, Thammasat University, Pathum Thani, Thailand.
Int J Rheum Dis. 2018 Jul;21(7):1458-1462. doi: 10.1111/1756-185X.13329.
Vanishing bone disease with multisystemic involvement may mimic systemic autoimmune or autoinflammatory diseases. We present a 19-year-old man who was hospitalized due to chest pain following a progressive osteolysis of the bony thorax. The disease later expanded into the pleura, peritoneum and pericardium in a form of massive chylous polyserositis. The patient also developed thrombosis of multiple central veins, which in turn worsened the chylothorax by increasing the pressure in the thoracic duct. This is the first case of vanishing bone disease complicated by triple chylous effusions and central vein thrombosis.
伴有多系统受累的骨质溶解症可能酷似系统性自身免疫性或自身炎症性疾病。我们报告一名19岁男性，因胸廓进行性骨质溶解后出现胸痛而住院。该疾病随后以大量乳糜性多浆膜炎的形式扩展至胸膜、腹膜和心包。患者还出现了多条中心静脉血栓形成，进而通过增加胸导管压力使乳糜胸恶化。这是首例伴有三联乳糜性积液和中心静脉血栓形成的骨质溶解症病例。
