Jin Lei, Yang Hong-Yu, Wang Yu-Fan, Yang Hui-Jun
Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518001; Department of Stomatology, Anhui Medical University, Hefei, Anhui, 230000, P.R. China.
Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518001, China.
J Cancer Res Ther. 2018 Jun;14(Supplement):S542-S543. doi: 10.4103/0973-1482.176180.
Adult fibrosarcoma (FS) of the maxillary sinus and the cranial base is a rare soft tissue sarcoma which is clinically characterized by a high frequency of local repeated recurrence if not excised widely. At present, the standard treatment option for FS is surgical resection. Here, we report a case of a 46-year-old male with a 5 months history recurrent FS of the maxillary sinus. The patient possessed an enormous mass in the right maxillofacial region extending to the cranial base, as observed by computed tomography. Histologically, the lessions were composed of hypercellular cells with heterogenous groups. The recurrence and pathologically heterogenous groups of FS lead to therapeutic complexities. Due to the challenging anatomy in head and neck region, it is crucial to define the lesion areas and weigh the balance between life quality and functional reconstruction.
上颌窦和颅底的成人纤维肉瘤（FS）是一种罕见的软组织肉瘤，其临床特征是如果不进行广泛切除，局部反复复发的频率很高。目前，FS的标准治疗选择是手术切除。在此，我们报告一例46岁男性，有上颌窦复发性FS病史5个月。计算机断层扫描显示，该患者右颌面部区域有一个巨大肿块，延伸至颅底。组织学上，病变由细胞过多的细胞和异质性群体组成。FS的复发和病理异质性群体导致治疗复杂性。由于头颈部区域解剖结构具有挑战性，确定病变区域并权衡生活质量和功能重建之间的平衡至关重要。
