早产儿的睡眠与唾液皮质醇：一项临床、随机、对照、交叉研究。
Sleep and salivary cortisol in preterm neonates: a clinical, randomized, controlled, crossover study.
作者信息
Araújo Fabrícia Magalhães, Pedreira Mavilde da Luz Gonçalves, Avelar Ariane Ferreira Machado, Pradella-Hallinan Márcia Lurdes de Cácia, Tsunemi Miriam Harumi, Pinheiro Eliana Moreira
机构信息
Universidade Federal de São Paulo, Escola Paulista de Enfermagem. São Paulo, Brazil.
Universidade Federal de São Paulo, Escola Paulista de Medicina. São Paulo, Brazil.
出版信息
Rev Bras Enferm. 2018;71(suppl 3):1358-1365. doi: 10.1590/0034-7167-2017-0546.
OBJECTIVE
Analyze the influence of ear protectors on the baseline levels of salivary cortisol and response and total sleep time of preterm neonates during two periods of environmental management of a neonatal intermediate care unit.
METHOD
A clinical, randomized, controlled and crossover study conducted with 12 preterm neonates. The use of ear protectors was randomized in two periods. Sleep evaluation was performed using one Alice 5 Polysomnography System and unstructured observation.
RESULTS
No significant difference was observed between the baseline levels of salivary cortisol and response in preterm neonates from the control and experimental groups, and no statistical significance was observed between the total sleep time of both groups. No relationship was observed between the baseline levels of cortisol and response and total sleep time.
CONCLUSION
Ear protectors in preterm neonates did not influence the salivary cortisol level and total sleep time in the studied periods.
目的
分析在新生儿中级护理单元的两个环境管理阶段，耳塞对早产儿唾液皮质醇基线水平、反应及总睡眠时间的影响。
方法
对12例早产儿进行一项临床、随机、对照和交叉研究。在两个阶段随机使用耳塞。使用一台Alice 5多导睡眠图系统和非结构化观察进行睡眠评估。
结果
对照组和实验组早产儿的唾液皮质醇基线水平及反应之间未观察到显著差异，两组的总睡眠时间之间也未观察到统计学意义。皮质醇基线水平及反应与总睡眠时间之间未观察到相关性。
结论
在所研究的阶段，早产儿使用耳塞不影响唾液皮质醇水平和总睡眠时间。
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