Loder Elizabeth, Weizenbaum Emma, Giddon Donald
Division of Headache, Department of Neurology, Brigham and Women's Faulkner Hospital, Harvard Medical School, Boston, MA, USA.
John R. Graham Headache Center, Brigham and Women's Faulkner Hospital, Boston, MA, USA.
Pain Res Manag. 2018 Jun 4;2018:6157982. doi: 10.1155/2018/6157982. eCollection 2018.
Lateralized pain is a core diagnostic feature of migraine. In previous research, left-sided spinal pain was more frequent and associated with greater emotional distress and healthcare use than right-sided pain. We hypothesized therefore that patients with left-sided head pain might experience higher levels of distress or healthcare use than those with right-sided or bilateral pain.
Medical record information was extracted for 477 randomly selected patients with migraine seen in 2011 in a tertiary headache clinic. This included demographic data, pain location, handedness, comorbid psychiatric diagnoses, medical and emergency department visits, and use of selected headache medications.
Two hundred twenty-eight of four hundred seventy-seven (47.8%) patients reported lateralized pain, of which 107 (47.9%) patients were right sided compared with 65 (28.5%) left-sided patients (=0.001), while 56 (24.5%) reported unilateral pain with no side predominance. Contrary to expectations, with the exception of self-reported posttraumatic stress disorder, there were no statistically significant differences between left and right in measures of psychiatric distress, emergency department visits, or healthcare use.
Although unilateral pain location can be helpful in making a migraine diagnosis, it does not appear to have additional clinical implications. Additionally, its absence does not rule out a diagnosis of migraine since more than half of migraineurs have bilateral head pain.
偏侧性疼痛是偏头痛的核心诊断特征。在先前的研究中,左侧脊柱疼痛比右侧疼痛更常见,且与更严重的情绪困扰和医疗保健使用相关。因此,我们假设左侧头痛患者可能比右侧或双侧头痛患者经历更高水平的困扰或医疗保健使用。
提取了2011年在一家三级头痛诊所随机选取的477例偏头痛患者的病历信息。这包括人口统计学数据、疼痛部位、利手、合并的精神疾病诊断、医疗和急诊科就诊情况以及所选头痛药物的使用情况。
477例患者中有228例(47.8%)报告有偏侧性疼痛,其中107例(47.9%)为右侧疼痛,而左侧疼痛患者有65例(28.5%)(=0.001),56例(24.5%)报告为无优势侧的单侧疼痛。与预期相反,除了自我报告的创伤后应激障碍外,在精神困扰、急诊科就诊或医疗保健使用方面,左右侧之间没有统计学上的显著差异。
虽然单侧疼痛部位有助于偏头痛诊断,但似乎没有其他临床意义。此外,没有单侧疼痛并不排除偏头痛的诊断,因为超过一半的偏头痛患者有双侧头痛。