Neurological Department -ASL, Caltanissetta, Italy.
Child Neuropsychiatry Unit Department, Pro.M.I.S.E. "G D'Alessandro", University of Palermo, Palermo, Italy.
Neurol Sci. 2021 Jul;42(7):2965-2968. doi: 10.1007/s10072-021-05111-7. Epub 2021 Feb 6.
Migraine is a typically unilateral disorder in adulthood; however, the reasons for painful lateralization have been little investigated. The possible influence of manual dominance was suggested. We aimed to investigate the localization of pain in migraine attacks in right-handed and left-handed subjects. The retrospective study collected 546 patients with migraine aged between 16 and 65 years, reporting the manual dominance to the Edinburgh test. We included 466 right-handed and 80 left-handed subjects with migraine. We registered 4215 unilateral painful attacks. The right-handers had 3412 unilateral episodes; 62.8% of the attacks were characterized by pain on the right side and 37.2% by pain on the left. The left-handed subjects reported 803 unilateral pain with 63.5% of unilateral pain episodes on the left side and 36.5% of attacks with lateralized pain on the right (p < 0.001). Our data suggest that manual dominance may influence the side of pain lateralization in migraine.
偏头痛在成年期通常是单侧疾病；然而，疼痛侧化的原因还很少被研究。有人提出了手性优势的可能影响。我们旨在研究右利手和左利手偏头痛患者偏头痛发作时疼痛的定位。这项回顾性研究收集了 546 名年龄在 16 至 65 岁之间、向爱丁堡测试报告手性优势的偏头痛患者。我们纳入了 466 名右利手和 80 名左利手偏头痛患者。我们记录了 4215 次单侧疼痛发作。右利手患者有 3412 次单侧发作；62.8%的发作表现为右侧疼痛，37.2%的发作表现为左侧疼痛。左利手患者报告了 803 次单侧疼痛，其中 63.5%的单侧疼痛发作发生在左侧，36.5%的发作表现为右侧疼痛偏侧化（p<0.001）。我们的数据表明，手性优势可能影响偏头痛疼痛侧化的侧别。
