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单双管输尿管支架置入术治疗恶性输尿管梗阻的比较:104 例前瞻性研究。

Comparison of single and tandem ureteral stenting for malignant ureteral obstruction: a prospective study of 104 patients.

机构信息

Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, No.7, Chung-Shan South Road, Taipei, 100, Taiwan.

Department of Medical Imaging, National Taiwan University Hospital Yunlin Branch, No. 579, Sec. 2, Yunlin Rd, Douliu City, Yunlin County, 640, Taiwan.

出版信息

Eur Radiol. 2019 Feb;29(2):628-635. doi: 10.1007/s00330-018-5560-6. Epub 2018 Jul 4.

Abstract

OBJECTIVES

The aim of this study was to compare single and tandem ureteral stenting in the management of malignant ureteral obstruction (MUO).

METHODS

Our hospital's institutional review board approved this prospective study. Between November 2014 and June 2017, single ureteral stenting was performed in 56 patients (94 renal units) and tandem ureteral stenting in 48 patients (63 renal units) for MUO. A comparative analysis of the technical success rate, patient survival, stent patency, and complications was performed.

RESULTS

Similar demographic data were observed in patients receiving either single or tandem ureteral stenting. The technical success rate was 93.6% (88/94) for single ureteral stenting and 95.2% (60/63) for tandem ureteral stenting. There was no difference in overall survival between patients receiving single or tandem ureteral stenting (p = 0.41), but the duration of stent patency in tandem ureteral stenting was significantly longer (p = 0.022). The mean patency time was 176.7 ± 21.3 days for single ureteral stenting, and 214.7 ± 21.0 days for tandem ureteral stenting. The complications of ureteral stenting were urinary tract infection (n = 18), lower urinary tract symptoms (n = 5), haematuria (n = 3), and stent migration (n = 1).

CONCLUSIONS

Tandem ureteral stenting is a safe and feasible treatment for MUO, and had better efficacy compared to single ureteral stenting.

KEY POINTS

• Ureteral stenting is an established treatment for the management of malignant ureteral obstruction (MUO) • Prospective single-centre study showed that tandem ureteral stenting is a safe and feasible treatment for MUO • Tandem ureteral stenting provides longer stent patency compared to single ureteral stenting in patient with MUO.

摘要

目的

本研究旨在比较单支和双支输尿管支架置入术在治疗恶性输尿管梗阻(MUO)中的效果。

方法

本研究经我院机构审查委员会批准,2014 年 11 月至 2017 年 6 月,56 例 MUO 患者(94 个肾脏单位)接受单支输尿管支架置入术,48 例 MUO 患者(63 个肾脏单位)接受双支输尿管支架置入术。对两组患者的技术成功率、患者生存情况、支架通畅率和并发症进行了对比分析。

结果

接受单支和双支输尿管支架置入术的患者具有相似的人口统计学数据。单支输尿管支架置入术的技术成功率为 93.6%(88/94),双支输尿管支架置入术的技术成功率为 95.2%(60/63)。两组患者的总体生存率无差异(p = 0.41),但双支输尿管支架置入术的支架通畅时间明显更长(p = 0.022)。单支输尿管支架置入术的平均通畅时间为 176.7 ± 21.3 天,双支输尿管支架置入术的平均通畅时间为 214.7 ± 21.0 天。输尿管支架置入术的并发症包括尿路感染(n = 18)、下尿路症状(n = 5)、血尿(n = 3)和支架移位(n = 1)。

结论

双支输尿管支架置入术是 MUO 的一种安全且可行的治疗方法,与单支输尿管支架置入术相比,疗效更好。

关键点

  1. 输尿管支架置入术是治疗恶性输尿管梗阻(MUO)的一种既定方法。

  2. 前瞻性单中心研究表明,双支输尿管支架置入术是 MUO 的一种安全且可行的治疗方法。

  3. 与单支输尿管支架置入术相比,双支输尿管支架置入术可为 MUO 患者提供更长的支架通畅时间。

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