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恶性输尿管梗阻的支架置入术:串联式、金属或金属网支架。

Stenting for malignant ureteral obstruction: Tandem, metal or metal-mesh stents.

作者信息

Elsamra Sammy E, Leavitt David A, Motato Hector A, Friedlander Justin I, Siev Michael, Keheila Mohamed, Hoenig David M, Smith Arthur D, Okeke Zeph

机构信息

The Smith Institute for Urology, Hofstra-North Shore-LIJ Health System, New Hyde Park, New York, USA.

出版信息

Int J Urol. 2015 Jul;22(7):629-36. doi: 10.1111/iju.12795. Epub 2015 May 6.

Abstract

Extrinsic malignant compression of the ureter is not uncommon, often refractory to decompression with conventional polymeric ureteral stents, and frequently associated with limited survival. Alternative options for decompression include tandem ureteral stents, metallic stents and metal-mesh stents, though the preferred method remains controversial. We reviewed and updated our outcomes with tandem ureteral stents for malignant ureteral obstruction, and carried out a PubMed search using the terms "malignant ureteral obstruction," "tandem ureteral stents," "ipsilateral ureteral stents," "metal ureteral stent," "resonance stent," "silhouette stent" and "metal mesh stent." A comprehensive review of the literature and summary of outcomes is provided. The majority of studies encountered were retrospective with small sample sizes. The evidence is most robust for metal stents, whereas only limited data exists for tandem or metal-mesh stents. Metal and metal-mesh stents are considerably more expensive than tandem stenting, but the potential for less frequent stent exchanges makes them possibly cost-effective over time. Urinary tract infections have been associated with all stent types. A wide range of failure rates has been published for all types of stents, limiting direct comparison. Metal and metal-mesh stents show a high incidence of stent colic, migration and encrustation, whereas tandem stents appear to produce symptoms equivalent to single stents. Comparison is difficult given the limited evidence and heterogeneity of patients with malignant ureteral obstruction. It is clear that prospective, randomized studies are necessary to effectively scrutinize conventional, tandem, metallic ureteral and metal-mesh stents for their use in malignant ureteral obstruction.

摘要

输尿管的外在恶性压迫并不罕见,使用传统的聚合物输尿管支架减压往往难以奏效,且常与生存期有限相关。减压的替代选择包括串联输尿管支架、金属支架和金属网支架,尽管首选方法仍存在争议。我们回顾并更新了使用串联输尿管支架治疗恶性输尿管梗阻的结果,并在PubMed上使用“恶性输尿管梗阻”“串联输尿管支架”“同侧输尿管支架”“金属输尿管支架”“共振支架”“轮廓支架”和“金属网支架”等术语进行了检索。本文提供了对文献的全面综述和结果总结。大多数研究为回顾性研究,样本量较小。关于金属支架的证据最为充分,而关于串联或金属网支架的资料有限。金属和金属网支架比串联支架贵得多,但随着时间推移,支架更换频率较低可能使其具有成本效益。所有类型的支架都与尿路感染有关。所有类型支架的失败率报道范围很广,限制了直接比较。金属和金属网支架的支架绞痛、移位和结痂发生率较高,而串联支架产生的症状似乎与单个支架相当。鉴于证据有限以及恶性输尿管梗阻患者的异质性,比较困难。显然,需要进行前瞻性随机研究,以有效审查传统、串联、金属输尿管和金属网支架在恶性输尿管梗阻中的应用。

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