Bertolin-Colilla Marta, Alcalá Rebeca, Deza Gustavo, Polino Luciano, Gallardo Fernando, Pujol Ramon M
Department of Dermatology, Hospital del Mar, Barcelona, Spain.
Department of Rheumatology, Hospital del Mar, Barcelona, Spain.
Pediatr Dermatol. 2018 Sep;35(5):e291-e293. doi: 10.1111/pde.13592. Epub 2018 Jul 4.
Inflammatory linear verrucous epidermal nevus and linear psoriasis are different entities with clinical and histopathologic similarities. Isolated reports of inflammatory linear verrucous epidermal nevus with concomitant psoriasis or a positive family history of psoriasis have been described, and the possibility that inflammatory linear verrucous epidermal nevus may be a mosaic form of cutaneous psoriasis has been postulated. We report a 17-year-old boy with a congenital, linear, erythematous, keratotic plaque on the dorsum of the fifth finger of the left hand with ipsilateral nail dystrophy. Histopathologic examination showed epidermal hyperplasia with alternating orthokeratosis and parakeratosis. During follow-up, he developed erosive monoarthritis of the distal interphalangeal joint. This case seems to confirm the association between inflammatory linear verrucous epidermal nevus and arthritis and supports a possible relationship between inflammatory linear verrucous epidermal nevus and psoriasis.
炎性线状疣状表皮痣与线状银屑病是具有临床和组织病理学相似性的不同疾病。已有关于炎性线状疣状表皮痣合并银屑病或有银屑病家族史的孤立病例报道，并且有人推测炎性线状疣状表皮痣可能是皮肤银屑病的一种嵌合形式。我们报告一名17岁男孩，其左手小指背有一先天性、线状、红斑性、角化性斑块，并伴有同侧甲营养不良。组织病理学检查显示表皮增生，伴有正角化和不全角化交替。在随访期间，他出现了远端指间关节糜烂性单关节炎。该病例似乎证实了炎性线状疣状表皮痣与关节炎之间的关联，并支持炎性线状疣状表皮痣与银屑病之间可能存在的关系。
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