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由大肠杆菌引起的尿路感染的孕妇的母婴及围产期并发症

Maternal and perinatal complications in pregnant women with urinary tract infection caused by Escherichia coli.

作者信息

Dautt-Leyva José G, Canizalez-Román Adrian, Acosta Alfaro Luis F, Gonzalez-Ibarra Fernando, Murillo-Llanes Joel

机构信息

Department of Neonatology, Women's Hospital, Secretariat of Health, Sinaloa, Mexico.

Research Department, Faculty of Medicine, Autonomous University of Sinaloa, Sinaloa, Mexico.

出版信息

J Obstet Gynaecol Res. 2018 Aug;44(8):1384-1390. doi: 10.1111/jog.13687. Epub 2018 Jul 5.

DOI:10.1111/jog.13687
PMID:29974558
Abstract

AIM

The incidence of urinary tract infection (UTI) in pregnant women may vary from 5-10% and depends on parity, race, socioeconomic status and anatomical and functional changes in pregnancy. In Mexico, preterm birth accounts for 75% of perinatal deaths and 50% of the neurological sequelae attributable directly to prematurity. The objective of the present study is to describe maternal and perinatal complications in pregnant women with UTI caused by Escherichia coli and to find out the antimicrobial susceptibility pattern.

METHODS

A descriptive and longitudinal study of pregnant women admitted to the Women's Hospital in Culiacan, Sinaloa, Mexico, was carried out from January 2013 to December 2014. Patients with E. coli infection were included, and infections caused by other microorganisms were excluded. The sociodemographic variables, causes of hospitalization and the type of maternal and perinatal complications were determined.

RESULTS

The causes of admission to the hospital were threatened preterm labor, and fever and threatened abortion. Of 38 patients with threatened preterm labor, 33 went on to delivery, four were preterm births and two were neonatal deaths. E. coli was sensitive to over 90% of piperacillin-tazobactam, amikacin, nitrofurantoin and carbapenems.

CONCLUSION

According to this study in a Mexican population, the number one admission diagnosis in women with UTI due to E. coli was threatened preterm labor, and fever and threatened abortion. E. coli was sensitive to more than 90% of piperacillin-tazobactam, amikacin, nitrofurantoin and carbapenems.

摘要

目的

孕妇尿路感染(UTI)的发病率可能在5%至10%之间,且取决于产次、种族、社会经济地位以及孕期的解剖和功能变化。在墨西哥,早产占围产期死亡的75%,以及直接归因于早产的神经后遗症的50%。本研究的目的是描述由大肠杆菌引起的孕妇尿路感染的母体和围产期并发症,并找出抗菌药物敏感性模式。

方法

对2013年1月至2014年12月入住墨西哥锡那罗亚州库利亚坎市妇女医院的孕妇进行了一项描述性纵向研究。纳入大肠杆菌感染的患者,排除其他微生物引起的感染。确定了社会人口统计学变量、住院原因以及母体和围产期并发症的类型。

结果

入院原因是先兆早产、发热和先兆流产。在38例先兆早产患者中,33例继续分娩,4例早产,2例新生儿死亡。大肠杆菌对超过90%的哌拉西林 - 他唑巴坦、阿米卡星、呋喃妥因和碳青霉烯类药物敏感。

结论

根据这项针对墨西哥人群的研究,因大肠杆菌导致尿路感染的女性患者的首要入院诊断是先兆早产、发热和先兆流产。大肠杆菌对超过90%的哌拉西林 - 他唑巴坦、阿米卡星、呋喃妥因和碳青霉烯类药物敏感。

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