Lluch Taltavull Josep Ignasi, Mercadal Orfila Gabriel, Afonzo Gobbi Yashmin Silvana
Hospital General Mateu Orfila.
Nutr Hosp. 2018 May 10;35(3):606-611. doi: 10.20960/nh.1426.
to apply a protocol that facilitates the detection of malnutrition in cancer patients during their treatment of radiotherapy or chemotherapy, selecting those that could benefit from a specific nutritional intervention.
malnutrition was assessed with the Malnutrition Screening Tool (MST). Patients at malnutrition risk were evaluated with patient generated subjective-global assessment (PG-SGA) and a subgroup of the sample studied was also assessed with a quality of life (CV) using the EORTC QLQ-C30 questionnaire.
from 222 patients, risk of malnutrition was observed in 126 (56.7%). The PG-SGA shows an initial prevalence of malnutrition of 69.2% (61.7% moderately malnourished and 7.5% severe malnutrition) and a mean weight loss of -10.27 kg. In the last evaluation (+12 months), the percentage of malnutrition or risk was significantly reduced to 23.5% and the mean weight loss decreased to -7.1 kg. During follow-up, the scores of the EORTC QLQ-C30 questionnaire improved, especially at three months on the diarrhea scale (p = 0.037), at six months on the pain scale (p = 0.009), and at 12 months on the pain (p = 0.026), nausea and vomiting (p = 0.002), dyspnea (p = 0.016), loss of appetite (p = 0.002) and constipation (p = 0.05) scales.
the protocol has been effective in improving the nutritional status and quality of life of cancer patients with partial recovery of lost weight.
应用一种方案,以促进在癌症患者接受放疗或化疗期间检测营养不良情况,筛选出那些可从特定营养干预中获益的患者。
采用营养不良筛查工具(MST)评估营养不良情况。对存在营养不良风险的患者采用患者主观整体评定法(PG-SGA)进行评估,并且使用欧洲癌症研究与治疗组织生活质量问卷(EORTC QLQ-C30)对样本中的一个亚组进行生活质量(CV)评估。
在222例患者中,观察到126例(56.7%)存在营养不良风险。PG-SGA显示初始营养不良患病率为69.2%(中度营养不良占61.7%,重度营养不良占7.5%),平均体重减轻-10.27千克。在最后一次评估(+12个月)时,营养不良或风险百分比显著降至23.5%,平均体重减轻降至-7.1千克。在随访期间,EORTC QLQ-C30问卷得分有所改善,尤其是在三个月时腹泻量表得分(p = 0.037)、六个月时疼痛量表得分(p = 0.009)以及12个月时疼痛(p = 0.026)、恶心和呕吐(p = 0.002)、呼吸困难(p = 0.016)、食欲减退(p = 0.002)和便秘(p = 0.05)量表得分。
该方案在改善癌症患者营养状况和生活质量以及部分恢复体重方面有效。