Nepal Family Development Foundation, Kathmandu, Nepal.
Ministry of Health, Kathmandu, Nepal.
BMC Complement Altern Med. 2018 Jul 5;18(1):207. doi: 10.1186/s12906-018-2275-9.
Hypertension control remains a major global challenge. The behavioral approaches recommended for blood pressure reduction are stress reduction, increased exercise and healthy dietary habits. Some study findings suggest that yoga has a beneficial effect in reducing blood pressure. However, the role of yoga on blood pressure has received little attention in existing health care practices in developing countries. This study will be conducted in primary health care facilities in Nepal to assess the effectiveness of a pragmatic yoga intervention to complement standard practice in further reducing blood pressure.
This will be multicentric, two arms, randomized, nonblinded, pragmatic trial. It will be conducted in seven District Ayurveda Health Centers (DAHCs) in Nepal between July 2017 and June 2018. The study participants will consist of hypertensive patients with or without antihypertensive medication attending to the outpatient department (OPD). One hundred and forty participants will be randomized to treatment or control groups by using a stratified block randomization. At the study site, the treatment arm participants will receive an intervention consisting of five days of structured yoga training and practice of the same package at home with a recommendation of five days a week for the following 90 days. Both the intervention and control groups will receive two hours of health education on lifestyle modifications. The primary outcome of this trial will be the change in systolic blood pressure and it will be assessed after 90 days of the intervention.
This study will establish the extent to which a yoga intervention package can help reduce blood pressure in hypertensive patients. If proven effective, study findings may be used to recommend the governing bodies and other stakeholders for the integration of yoga in the national healthcare system for the treatment and control of hypertension.
Clinical Trial Registry- India (CTRI); CTRI Reg. No- CTRI/2017/02/007822 . Registered on 10/02/2017.
高血压的控制仍然是一个全球性的主要挑战。推荐用于降低血压的行为方法包括减轻压力、增加运动和健康的饮食习惯。一些研究结果表明，瑜伽对降低血压有有益的影响。然而，瑜伽对血压的作用在发展中国家现有的医疗保健实践中很少受到关注。本研究将在尼泊尔的基层医疗保健机构进行，以评估实用瑜伽干预在进一步降低血压方面补充标准实践的效果。
这将是一项多中心、双盲、随机、实用的试验。它将在尼泊尔的七个地区 Ayurveda 保健中心（DAHCs）进行，时间为 2017 年 7 月至 2018 年 6 月。研究参与者将包括在门诊部门（OPD）就诊的高血压患者，无论是否服用抗高血压药物。将使用分层块随机化方法将 140 名参与者随机分为治疗组或对照组。在研究现场，治疗组的参与者将接受为期五天的结构化瑜伽训练和在家中练习同一方案的建议，为期 90 天，每周五天。干预组和对照组都将接受两小时的生活方式改变健康教育。本试验的主要结局是干预 90 天后收缩压的变化。
本研究将确定瑜伽干预方案在降低高血压患者血压方面的效果。如果被证明有效，研究结果可能被用于建议管理机构和其他利益相关者将瑜伽纳入国家医疗保健系统，以治疗和控制高血压。
印度临床试验注册处（CTRI）；CTRI 注册号- CTRI/2017/02/007822. 于 2017 年 2 月 10 日注册。
