University Clinic for Gynaecology and Perinatology, Maribor University Medical Centre, Ljubljanska 5, SI-2000 Maribor, Slovenia.
Nutrients. 2018 Jul 5;10(7):867. doi: 10.3390/nu10070867.
The association between vitamin D deficiency and various adverse pregnancy outcomes has been extensively investigated in recent years. The pregnant woman is the only source of vitamin D for the foetus. The main sources of vitamin D for pregnant women are sunlight, fortified dairy products, oily fish and dietary supplements. Vitamin D deficiency during pregnancy has been associated with some adverse neonatal outcomes as well as an increased risk of late pregnancy complications. The outcomes of the published studies investigating preeclampsia and gestational diabetes mellitus vary with some large trials suggesting a potential positive effect of vitamin D supplementation during pregnancy on the decreased risk of these complications. Research also suggests a possible connection between lower vitamin D concentrations and increased risk of preterm labour. In our manuscript, we aim to review the existing literature regarding the prevalence of vitamin D deficiency during pregnancy, the factors associated with vitamin D deficiency, and possible pregnancy complications arising from it.
近年来，维生素 D 缺乏与各种不良妊娠结局之间的关系已得到广泛研究。孕妇是胎儿维生素 D 的唯一来源。孕妇维生素 D 的主要来源是阳光、强化乳制品、油性鱼类和膳食补充剂。妊娠期间维生素 D 缺乏与一些不良新生儿结局以及妊娠晚期并发症风险增加有关。研究子痫前期和妊娠期糖尿病的已发表研究结果各不相同，一些大型试验表明，妊娠期间补充维生素 D 可能降低这些并发症的风险。研究还表明，维生素 D 浓度较低与早产风险增加之间可能存在关联。在我们的论文中，我们旨在回顾关于妊娠期间维生素 D 缺乏的流行率、与维生素 D 缺乏相关的因素以及由此产生的可能的妊娠并发症的现有文献。
