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胃冬眠瘤:一种罕见肿瘤的新发病部位及表现

Gastric hibernoma: a novel location and presentation of a rare tumor.

作者信息

Smith Shane P, Feczko Andrew F, Mihura Matias, Chen Jey-Hsin, Farivar Alexander S

机构信息

Department of Thoracic Surgery, Swedish Medical Center, Seattle, WA, USA.

Department of Pathology, CellNetix, Seattle, WA, USA.

出版信息

J Surg Case Rep. 2018 May 22;2018(5):rjy105. doi: 10.1093/jscr/rjy105. eCollection 2018 May.

DOI:10.1093/jscr/rjy105
PMID:29977506
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6007422/
Abstract

We present a case of gastric hibernoma, an unusual tumor with a location novel to the literature. A 39-year-old female presented with one year of upper gastrointestinal bleeding and dysphagia. Gastroenterology performed an esophagogastroduodenoscopy with ultrasound and identified a 6 cm mass within the muscularis propria of the antrum. Computed tomography demonstrated a 9.7 × 7.8 × 4.8 cm heterogeneous antral mass with internal septa. A distal gastrectomy with Bilroth I gastroduodenostomy was performed with 4 cm proximal and 2 cm distal margins. Excision was appropriate to make the diagnosis, exclude malignancy, and remove a symptomatic mass. Hibernoma was confirmed by histopathology. These are rare tumors of brown fat named for their resemblance to the thermogenic tissue found in hibernating animals. They typically present as a slowly enlarging mass of the thigh or shoulder. To our knowledge, this is the first presentation of a hibernoma as a submucosal gastric mass.

摘要

我们报告一例胃冬眠瘤,这是一种罕见肿瘤,其位置在文献中尚无先例。一名39岁女性,有一年的上消化道出血和吞咽困难症状。胃肠病科进行了超声食管胃十二指肠镜检查,发现胃窦固有肌层内有一个6厘米的肿块。计算机断层扫描显示一个9.7×7.8×4.8厘米的胃窦部不均匀肿块,内部有分隔。行毕罗一式胃十二指肠吻合术的远端胃切除术,切缘近端4厘米、远端2厘米。切除手术对于明确诊断、排除恶性肿瘤以及切除有症状的肿块是合适的。组织病理学确诊为冬眠瘤。这些是棕色脂肪的罕见肿瘤,因其与冬眠动物体内的产热组织相似而得名。它们通常表现为大腿或肩部缓慢增大的肿块。据我们所知,这是首例以胃黏膜下肿块形式出现的冬眠瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/1847c79a2394/rjy105f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/f2ba03433371/rjy105f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/260a818161c1/rjy105f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/1847c79a2394/rjy105f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/f2ba03433371/rjy105f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/260a818161c1/rjy105f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed6e/6007422/1847c79a2394/rjy105f03.jpg

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A Diagnostic Dilemma of a Subcutaneous Hibernoma: Case Report.皮下脂肪瘤的诊断难题:病例报告。
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本文引用的文献

1
Hibernoma Showing High Uniform Accumulation on an F-Fluorodeoxyglucose Positron Emission Tomography Scan: A Case Report.18F-氟脱氧葡萄糖正电子发射断层扫描显示高均匀性摄取的冬眠瘤:一例报告
Case Rep Oncol. 2016 Aug 17;9(2):427-431. doi: 10.1159/000448240. eCollection 2016 May-Aug.
2
The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma.18F-氟脱氧葡萄糖正电子发射断层显像/计算机断层扫描(FDG-PET/CT)诊断冬眠瘤的价值与局限性
Case Rep Orthop. 2015;2015:958690. doi: 10.1155/2015/958690. Epub 2015 Dec 13.
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Symptomatic hibernoma: a rare soft tissue tumor.
症状性冬眠瘤:一种罕见的软组织肿瘤。
Hawaii J Med Public Health. 2012 Dec;71(12):342-5.
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Massive abdominal wall hibernoma: case report and literature review of a rare soft-tissue tumor.巨大腹壁冬眠瘤:一种罕见软组织肿瘤的病例报告及文献复习。
J Natl Med Assoc. 2011 Apr;103(4):372-4. doi: 10.1016/s0027-9684(15)30320-5.
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Hibernoma of the neck: a rare cause of neck mass.颈部冬眠瘤:颈部肿块的罕见病因。
Am J Otolaryngol. 1994 Mar-Apr;15(2):152-4. doi: 10.1016/0196-0709(94)90066-3.
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Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study.急性上消化道出血住院治疗的流行病学:一项基于人群的研究。
Am J Gastroenterol. 1995 Feb;90(2):206-10.