Jan Kalimullah, Chuin Siau
Department of Medicine, Changi General Hospital Singapore, 2 Simei Street 3, Singapore, Singapore.
Centre for Performance Excellence, Changi General Hospital, Singapore, 2 Simei Street 3, Singapore, Singapore.
Oxf Med Case Reports. 2018 Jun 25;2018(6):omy025. doi: 10.1093/omcr/omy025. eCollection 2018 Jun.
Transient global amnesia (TGA) is a syndrome characterized by reversible impairment of short-term memory. TGA itself is a benign disease, however, it is reasonable to investigate and exclude sinister causes of global amnesia; such as stroke or a seizure activity. A case of TGA is presented here with special emphasis on the typical TGA lesion that was detected on the patient's magnetic resonance imaging (MRI) of Brain. In patients with TGA, the typical MRI Brain finding is a tiny focus of diffusion restriction in the mesiotemporal lobe. This finding can potentially aid in early diagnosis and management of TGA. Although in overwhelming majority of cases, the TGA episode occurs only once, yet a second TGA episode can occur rarely. This patient, two years later, had a recurrence of TGA episode, albeit with a normal MRI brain, and without residual changes from prior episode.
短暂性全面性遗忘症（TGA）是一种以短期记忆可逆性损害为特征的综合征。TGA本身是一种良性疾病，然而，对全面性遗忘症的潜在严重病因进行调查并排除是合理的，例如中风或癫痫活动。本文介绍了一例TGA病例，特别强调了在患者脑部磁共振成像（MRI）上检测到的典型TGA病变。在TGA患者中，典型的脑部MRI表现是颞叶内侧出现一个微小的弥散受限灶。这一发现可能有助于TGA的早期诊断和治疗。尽管在绝大多数情况下，TGA发作仅发生一次，但第二次TGA发作很少见。该患者在两年后再次出现TGA发作，尽管脑部MRI正常，且没有上次发作的残留改变。
