Demas Alexis, Bennani Omar, Vandendriessche Anne, de Menibus Laurence Hellouin, Langlois Vincent, Gasnault Jacques
Department of Neurology, Hospital Jacques Monod, Le Havre, France.
Department of Infectious Diseases and Internal Medicine, Hospital Jacques Monod, Le Havre, France.
Open Forum Infect Dis. 2018 May 21;5(6):ofy112. doi: 10.1093/ofid/ofy112. eCollection 2018 Jun.
Neurological opportunistic infections are going to increase. Clinicians should be aware of the neurological spectrum of JC virus manifestations, including granule cell neuronopathy. Detection of JC virus DNA by polymerase chain reaction in cerebrospinal fluid should be realized in the assessment of a progressive cerebellar ataxia in an immunocompromised patient.
神经系统机会性感染将会增加。临床医生应了解JC病毒表现的神经学范围,包括颗粒细胞神经元病。在评估免疫功能低下患者的进行性小脑共济失调时,应通过聚合酶链反应检测脑脊液中的JC病毒DNA。