Zhang Zhenming, Wang Hui, Qiu Nianli, Kong Yujing, Zeng Wenjuan, Zhang Yongquan, Zhao Junfeng
Key Laboratory of Chemical Biology of Jiangxi Province, College of Chemistry and Chemical Engineering , Jiangxi Normal University , Nanchang 330022 , P.R. China.
J Org Chem. 2018 Aug 3;83(15):8710-8715. doi: 10.1021/acs.joc.8b00965. Epub 2018 Jul 18.
An efficient palladium-catalyzed Suzuki coupling of 1,1-diarylmethyl-trimethylammonium triflates with arylboronic acids is reported. This reaction offers a novel approach to triarylmethane derivatives in good to excellent yields with the palladium-catalyzed C-N bond cleavage as the key feature. Broad substrate scope regarding both reaction partners are observed. Moreover, reactive functional groups such as vinyl and formyl groups are conserved in this transformation.
据报道，钯催化1,1 - 二芳基甲基三氟甲磺酸三甲铵与芳基硼酸进行高效的铃木偶联反应。该反应提供了一种制备三芳基甲烷衍生物的新方法，产率良好至优异，其关键特征是钯催化的C-N键裂解。观察到两种反应底物都具有广泛的底物范围。此外，乙烯基和甲酰基等活性官能团在该转化过程中得以保留。
