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门诊手部手术中的多模式疼痛控制

Multi-Modal Pain Control in Ambulatory Hand Surgery.

作者信息

Harrison Ryan K, DiMeo Teresa, Klinefelter Ryan D, Ruff Michael E, Awan Hisham M

机构信息

The Ohio State University Wexner Medical Center, Department of Orthopaedics, Columbus, OH.

出版信息

Am J Orthop (Belle Mead NJ). 2018 Jun;47(6). doi: 10.12788/ajo.2018.0042.

Abstract

We evaluated postoperative pain control and narcotic usage after thumb carpometacarpal (CMC) arthroplasty or open reduction and internal fixation (ORIF) of the distal radius in patients given opiates with or without other non-opiate medication using a specific dosing regimen. A prospective, randomized study of 79 patients undergoing elective CMC arthroplasty or ORIF of the distal radius evaluated postoperative pain in the first 5 postoperative days. Patients were divided into 4 groups: Group 1, oxycodone and acetaminophen PRN; Group 2, oxycodone and acetaminophen with specific dosing; Group 3, oxycodone, acetaminophen, and OxyContin with specific dosing; and Group 4, oxycodone, acetaminophen, and ketorolac with specific dosing. During the first 5 postoperative days, we recorded pain levels according to a numeric pain scale, opioid usage, and complications. Although differences in our data did not reach statistical significance, overall pain scores, opioid usage, and complication rates were less prevalent in the oxycodone, acetaminophen, and ketorolac group. Postoperative pain following ambulatory hand and wrist surgery under regional anesthesia was more effectively controlled with fewer complications using a combination of oxycodone, acetaminophen, and ketorolac with a specific dosing regimen.

摘要

我们采用特定给药方案,评估了在使用或未使用其他非阿片类药物的情况下,给予阿片类药物的患者在拇指腕掌关节(CMC)置换术或桡骨远端切开复位内固定术(ORIF)后的术后疼痛控制及阿片类药物使用情况。一项针对79例行择期CMC置换术或桡骨远端ORIF的患者的前瞻性随机研究,评估了术后前5天的疼痛情况。患者被分为4组:第1组,按需使用羟考酮和对乙酰氨基酚;第2组,按特定剂量使用羟考酮和对乙酰氨基酚;第3组,按特定剂量使用羟考酮、对乙酰氨基酚和奥施康定;第4组,按特定剂量使用羟考酮、对乙酰氨基酚和酮咯酸。在术后前5天,我们根据数字疼痛量表记录疼痛程度、阿片类药物使用情况及并发症。尽管我们的数据差异未达到统计学意义,但羟考酮、对乙酰氨基酚和酮咯酸组的总体疼痛评分、阿片类药物使用及并发症发生率更低。采用特定给药方案联合使用羟考酮、对乙酰氨基酚和酮咯酸,可更有效地控制区域麻醉下门诊手部和腕部手术后的疼痛,且并发症更少。

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