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鼻内镜下经鼻上颌动脉结扎联合低温等离子技术可在不进行术前栓塞的情况下完整切除晚期青少年鼻咽血管纤维瘤。

Endoscopic endonasal transmaxillary ligation of a feeding artery and coblation plasma technology enables en bloc resection of advanced juvenile nasopharyngeal angiofibroma without preoperative embolization.

作者信息

Morishita Hiroyuki, Kobayashi Masayoshi, Takeuchi Kazuhiko

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

Department of Otorhinolaryngology-Head and Neck Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

出版信息

Auris Nasus Larynx. 2019 Apr;46(2):306-310. doi: 10.1016/j.anl.2018.06.007. Epub 2018 Jul 3.

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a hypervascular tumor and uncontrolled hemorrhage makes its removal very difficult. Although preoperative intravascular embolization of a feeding artery is recommended, serious complications such as iatrogenic thrombosis in the brain and insufficient decrease in blood flow to the tumor are concerns. Recently, coblation plasma technology has been reported to be useful for tumor removal with minimum hemorrhage under a clear surgical field. Here we report successful removal of advanced JNA without preoperative embolization, using intraoperative ligation of the maxillary artery and coblation plasma technology. The left nasal cavity of a 23-years-old man was closed by a JNA tumor at Radkowski stage IIC, which was 65mm in size and extended from the nasal cavity to the infratemporal fossa. MRA imaging showed the maxillary artery running along the posterior wall of the maxillary sinus. Therefore, the maxillary artery was first clipped using an endoscopic modified medial maxillectomy (EMMM) approach and endoscopic endonasal en bloc resection of the tumor was then completed using coblation technology with no need for blood transfusion. This case illustrates that preoperative embolization is dispensable in JNA surgery even at Stage IIC if the maxillary artery can be ligated during surgery and a coblation device can be utilized.

摘要

青少年鼻咽血管纤维瘤(JNA)是一种血管丰富的肿瘤,难以控制的出血使其切除非常困难。尽管建议对供血动脉进行术前血管内栓塞,但诸如脑内医源性血栓形成和肿瘤血流减少不足等严重并发症令人担忧。最近,据报道,等离子消融技术有助于在清晰的手术视野下以最小的出血切除肿瘤。在此,我们报告了在未进行术前栓塞的情况下,通过术中结扎上颌动脉和使用等离子消融技术成功切除晚期JNA的病例。一名23岁男性的左鼻腔被Radkowski IIC期的JNA肿瘤堵塞,肿瘤大小为65mm,从鼻腔延伸至颞下窝。磁共振血管造影(MRA)成像显示上颌动脉沿上颌窦后壁走行。因此,首先采用内镜改良上颌骨内侧切除术(EMMM)方法夹闭上颌动脉,然后使用等离子消融技术完成肿瘤的内镜鼻内整块切除,无需输血。该病例表明,在JNA手术中,即使处于IIC期,如果术中能够结扎上颌动脉并使用等离子消融设备,术前栓塞是不必要的。

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