Nunno Andrew, Johnson Mahlon D, Wu Guan, Li Yan Michael
Department of Neurosurgery, University of Rochester School of Medicine and Dentistry, Rochester, NY 14620, United States.
Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14620, United States.
J Clin Neurosci. 2018 Sep;55:109-112. doi: 10.1016/j.jocn.2018.06.035. Epub 2018 Jul 4.
Occurrences of metastatic prostate cancer imitating a subdural hematoma are limited to a small number of case reports, even though prostate cancer spreads to the dura more than other types of cancer. Here, we present the case of a 64 year-old male whose prostate carcinoma's metastasis mimicked a subdural hematoma, and he suffered a middle cerebral artery stroke. Prostate cancer's high rate of progression to the dura is disproportionate to its relatively low rate of brain metastasis. Furthermore, we explore the potential molecular implications of prostate cancer's propensity to spread to the dura.
尽管前列腺癌比其他类型的癌症更易扩散至硬脑膜，但转移性前列腺癌模仿硬脑膜下血肿的病例报告却很有限。在此，我们报告一例64岁男性，其前列腺癌转移表现类似硬脑膜下血肿，并伴有大脑中动脉中风。前列腺癌向硬脑膜进展的高发生率与其相对较低的脑转移率不相称。此外，我们还探讨了前列腺癌易于扩散至硬脑膜的潜在分子机制。
