Hudson G S, Bankier A T, Satchwell S C, Barrell B G
Virology. 1985 Nov;147(1):81-98. doi: 10.1016/0042-6822(85)90229-6.
The 12-kbp short unique region of the B95-8 Epstein-Barr virus (EBV) genome has been sequenced and analysed for latent and lytic cycle transcripts. Two latent and three late mRNAs have been detected, the largest of the late transcripts potentially encoding a 143-kDa protein. The region containing oriP, the putative origin of replication of the genome as a plasmid in latently infected B lymphocytes, is shown to contain 21 direct repeats of a 30-bp A+T-rich sequence and a related large inverted repeat.
对B95 - 8型爱泼斯坦-巴尔病毒(EBV)基因组的12千碱基对短独特区域进行了测序,并分析了其潜伏和裂解周期转录本。已检测到两种潜伏性和三种晚期mRNA,其中最大的晚期转录本可能编码一种143千道尔顿的蛋白质。在潜伏感染的B淋巴细胞中,作为质粒的基因组假定复制起点oriP所在区域显示含有21个30碱基对富含A + T序列的直接重复序列和一个相关的大反向重复序列。