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肌肉注射维生素D3对维生素D3缺乏奶牛血清维生素D代谢物和电解质的影响。

The effect of intramuscularly administered vitamin D3 on serum vitamin D metabolites and electrolytes in vitamin D3 deficient dairy cows.

作者信息

Sturén M

出版信息

Acta Vet Scand. 1985;26(2):179-90. doi: 10.1186/BF03546550.

DOI:10.1186/BF03546550
PMID:2998167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8202675/
Abstract

The effect of intramuscular administration of vitamin D (1×10 IU D/100 kg bodyweight) to 3 different dairy breeds on the serum levels of vitamin D, 25-OH-D, 25-OH-D, Ca, inorganic P and Mg was studied. The vitamin metabolites and the electrolytes were analysed on 9 occasions during a 36-day period. Vitamin D was analysed on 6 occasions during the same period. No significant breed differences were observed except for 25-OH-D (P ≤ 0.05). The D level rose in 1 day from < 2 ng/ml to 906 ng/ml and decreased to below 50 % of the peak level after 6 days. At the end of the experiment (day 36) vitamin D was < 2 ng/ml. 25-OH-D rose from < 2 ng/ml to 106 ng/ml in 6 days and stayed at this level during the whole experiment. 25-OH-D decreased from 16 ng/ml to 5 ng/ml during the observation period.

摘要

研究了对3种不同奶牛品种肌肉注射维生素D(1×10 IU D/100千克体重)对血清中维生素D、25-羟基维生素D、25-羟基维生素D、钙、无机磷和镁水平的影响。在36天的时间内分9次分析维生素代谢产物和电解质。同期分6次分析维生素D。除25-羟基维生素D外(P≤0.05),未观察到品种间的显著差异。维生素D水平在1天内从<2纳克/毫升升至906纳克/毫升,并在6天后降至峰值水平的50%以下。实验结束时(第36天)维生素D<2纳克/毫升。25-羟基维生素D在6天内从<2纳克/毫升升至106纳克/毫升,并在整个实验期间维持在该水平。在观察期内,25-羟基维生素D从16纳克/毫升降至5纳克/毫升。

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本文引用的文献

1
Clinical implications of measurements of circulating vitamin D metabolites.循环维生素D代谢产物测量的临床意义
Clin Endocrinol Metab. 1980 Mar;9(1):63-79. doi: 10.1016/s0300-595x(80)80021-1.
2
Quantitation of the main metabolites of vitamin D in a single serum sample. I. Extraction, separation and purification of metabolites.单次血清样本中维生素D主要代谢物的定量分析。I. 代谢物的提取、分离与纯化。
Clin Chim Acta. 1980 Jun 10;104(2):133-46. doi: 10.1016/0009-8981(80)90190-4.
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Comparative study of the affinity of the serum vitamin D-binding protein.血清维生素D结合蛋白亲和力的比较研究
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Determination of 25-hydroxyvitamin D3 in serum by high performance liquid chromatography and isotope dilution-mass spectrometry.高效液相色谱-同位素稀释质谱法测定血清中25-羟基维生素D3
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Vitamin D3 toxicity in dairy cows.
J Dairy Sci. 1982 May;65(5):749-59. doi: 10.3168/jds.S0022-0302(82)82263-7.
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[A field trial on the effect of vitamin D 3 against parturient paresis].[维生素D₃预防产乳热效果的田间试验]
Nord Vet Med. 1971 Jan;23(1):44-50.
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Breed differences in parturient paresis.分娩瘫痪的品种差异。
Vet Rec. 1971 Jun 26;88(26):695. doi: 10.1136/vr.88.26.695.
8
Trials with prophylactic treatment of parturient paresis.分娩瘫痪预防性治疗的试验。
Vet Rec. 1970 Nov 7;87(19):575-8 passim. doi: 10.1136/vr.87.19.575.
9
Crystalline vitamin D3 for the prevention of milk fever in cattle.结晶维生素D3预防奶牛产乳热
Vet Rec. 1967 Aug 12;81(7):161-2. doi: 10.1136/vr.81.7.161.
10
25-Hydroxyvitamin D transport in human plasma. Isolation and partial characterization of calcifidiol-binding protein.人血浆中25-羟基维生素D的转运。骨化二醇结合蛋白的分离及部分特性鉴定。
J Biol Chem. 1976 Aug 25;251(16):4803-9.