Peacock S, Weissbach H
Arch Biochem Biophys. 1985 Nov 15;243(1):315-9. doi: 10.1016/0003-9861(85)90801-x.
As reported previously, Integration Host Factor (IHF) stimulates cII expression but the stimulatory effect is prevented by the NusA protein (Peacock and Weissbach, 1985, Biochem. Biophys. Res. Commun. 127, 1026-1031). The interaction between IHF and the NusA protein has been investigated further in studies on the in vitro expression of the genes for the beta (rpoB) and sigma (rpoD) subunits of RNA polymerase, both known to be stimulated by NusA. The NusA stimulation of rpoD expression can be prevented by IHF, but IHF has no effect by itself on rpoD expression. IHF does not influence rpoB expression either in the presence or absence of NusA.
如先前报道，整合宿主因子（IHF）刺激cII表达，但NusA蛋白可阻止这种刺激作用（Peacock和Weissbach，1985年，《生物化学与生物物理研究通讯》127卷，1026 - 1031页）。在关于RNA聚合酶β（rpoB）和σ（rpoD）亚基基因的体外表达研究中，对IHF与NusA蛋白之间的相互作用进行了进一步研究，已知这两个亚基的表达均受NusA刺激。IHF可阻止NusA对rpoD表达的刺激作用，但IHF自身对rpoD表达无影响。无论有无NusA，IHF均不影响rpoB表达。
