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耳源性外侧窦血栓形成:15例患者回顾及治疗趋势变化

Otogenic Lateral Sinus Thrombosis: A Review of Fifteen Patients and Changing Trends in the Management.

作者信息

Raja Kalaiarasi, Parida Pradipta Kumar, Alexander Arun, Surianarayanan Gopalakrishnan

机构信息

Department of ENT, Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry, Puducherry, India.

Department of ENT, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

出版信息

Int Arch Otorhinolaryngol. 2018 Jul;22(3):208-213. doi: 10.1055/s-0037-1604198. Epub 2017 Jul 14.

Abstract

Otogenic lateral sinus thrombosis is a rare intracranial complication of otitis media in the modern age of antibiotic treatment, but it is potentially a dangerous complication.  The aim of this study is to focus on the various clinical presentations, management options and sequelae in a series of fifteen patients with otogenic lateral sinus thrombosis.  Retrospective chart review of inpatients treated for otogenic lateral sinus thrombosis at our tertiary care institution between 2010 and 2015.  A total of 15 patients (11 males and 4 females) with ages ranging from 9 to 60 years were diagnosed with otogenic lateral sinus thrombosis. The most commonly reported symptoms were headache, ear discharge and hard of hearing, which were experienced by all 15 (100%) patients. In contrast to previous studies found in the literature, 7 (47%) patients in our series presented with neck pain and neck abscess. Imaging studies and microbiological cultures were performed for all patients, who also underwent a mastoidectomy procedure. Internal jugular vein ligation was performed on 5 (33%) patients. Incision and drainage of the neck abscess was performed on 7 (47%) patients. All patients had a satisfactory resolution of their symptoms, and the mortality rate was of 0%.  Otogenic lateral sinus thrombosis, though a rare complication, can still occur; therefore, keeping a high level of suspicion is important, especially in developing countries. We also describe the patients with neck abscess associated with this rare condition. Combining parenteral antibiotics with surgical intervention is the treatment of choice.

摘要

在抗生素治疗的现代时代,耳源性外侧窦血栓形成是中耳炎一种罕见的颅内并发症,但它可能是一种危险的并发症。本研究的目的是关注15例耳源性外侧窦血栓形成患者的各种临床表现、治疗选择和后遗症。对2010年至2015年期间在我们三级医疗机构接受耳源性外侧窦血栓形成治疗的住院患者进行回顾性病历审查。共有15例患者(11例男性和4例女性)被诊断为耳源性外侧窦窦窦源性外侧窦血栓形成,年龄在9岁至60岁之间。最常报告的症状是头痛、耳漏和听力减退,所有15例(100%)患者均有这些症状。与文献中先前的研究不同,我们系列中的7例(47%)患者出现颈部疼痛和颈部脓肿。对所有患者进行了影像学检查和微生物培养,这些患者还接受了乳突切除术。5例(33%)患者进行了颈内静脉结扎术。7例(47%)患者进行了颈部脓肿切开引流术。所有患者的症状均得到满意缓解,死亡率为0%。耳源性外侧窦血栓形成虽然是一种罕见的并发症,但仍然可能发生;因此,保持高度怀疑很重要,尤其是在发展中国家。我们还描述了与这种罕见疾病相关的颈部脓肿患者。肠外抗生素与手术干预相结合是首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/467f/6033598/4142f354688f/10-1055-s-0037-1604198-i0660or-1.jpg

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