一例免疫功能正常成年人的致命性类圆线虫高度感染综合征并文献复习

Fatal Strongyloides hyperinfection syndrome in an immunocompetent adult with review of the literature.

作者信息

Chan Fiona L Y, Kennedy Brendan, Nelson Renjy

机构信息

Department of Infectious Diseases, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Communicable Disease Control Branch, Adelaide, South Australia, Australia.

出版信息

Intern Med J. 2018 Jul;48(7):872-875. doi: 10.1111/imj.13940.

DOI:10.1111/imj.13940

PMID:29984512

Abstract

Strongyloides hyperinfection syndrome is rarely described in immunocompetent individuals. We present a case of fatal Strongyloides hyperinfection syndrome, and a literature review identifying nine other cases occurring in immunocompetent individuals, highlighting the challenges of diagnosis and treatment in this setting. While overall mortality is lower compared to immunocompromised patients, fatal outcomes still occur. A high index of suspicion is required for early diagnosis and treatment.

摘要

免疫功能正常个体中很少描述到类圆线虫超感染综合征。我们报告一例致命的类圆线虫超感染综合征病例，并进行文献回顾，确定了其他9例发生在免疫功能正常个体中的病例，强调了这种情况下诊断和治疗的挑战。虽然与免疫功能低下患者相比总体死亡率较低，但仍会出现致命结果。早期诊断和治疗需要高度的怀疑指数。