Suppr超能文献

屠宰场工人患滤泡性淋巴瘤,成功经验性治疗空肠弯曲菌所致脾切除术后败血症

Successful Empiric Therapy for Postsplenectomy Sepsis with Campylobacter fetus in an Abattoir Worker with Follicular Lymphoma.

作者信息

Nakazawa Hideyuki, Nishina Sayaka, Sakai Hitoshi, Ito Toshiro, Ishida Fumihiro, Kitano Kiyoshi

机构信息

Division of Hematology, Department of Internal Medicine, Shinshu University School of Medicine, Japan.

Department of Hematology, NHO Matsumoto Medical Center, Japan.

出版信息

Intern Med. 2018 Nov 15;57(22):3329-3332. doi: 10.2169/internalmedicine.1031-18. Epub 2018 Jul 6.

Abstract

Asplenia may yield an increased risk of fulminant sepsis with various pathogens. Human infection with Campylobacter fetus is rare, but it often presents with non-gastrointestinal tract infection among immunocompromised individuals. A 55-year-old abattoir worker presented with a fever. He had had splenectomy for follicular lymphoma and rituximab maintenance therapy by four months before the presentation. Blood cultures yielded C. fetus, and the administration of meropenem dissolved the bacteremia. Further maintenance therapy was withheld, and no recurrence of infection has been observed for seven years. Asplenia, occupational exposure, and/or rituximab maintenance therapy might have been precipitating factors of this rare infection.

摘要

无脾可能会增加感染各种病原体导致暴发性败血症的风险。人感染胎儿弯曲杆菌很罕见,但在免疫功能低下的个体中常表现为非胃肠道感染。一名55岁的屠宰场工人出现发热症状。他因滤泡性淋巴瘤接受了脾切除术,并在出现症状前四个月接受了利妥昔单抗维持治疗。血培养发现胎儿弯曲杆菌,美罗培南治疗消除了菌血症。停止了进一步的维持治疗,七年来未观察到感染复发。无脾、职业暴露和/或利妥昔单抗维持治疗可能是这种罕见感染的诱发因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8bd/6287999/a256e8cdde8b/1349-7235-57-3329-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验