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骨盆骨折尿道损伤患者行内固定和耻骨上导管置入术后感染并发症的风险。

Risk of infectious complications in pelvic fracture urethral injury patients managed with internal fixation and suprapubic catheter placement.

机构信息

Department of Urology (N.V.J., B.B.V.), Harborview Medical Center at the University of Washington, Seattle, Washington; and Institute of Urology (A.J.V.), Lahey Hospital and Medical Center, Burlington, Massachusetts.

出版信息

J Trauma Acute Care Surg. 2018 Sep;85(3):536-540. doi: 10.1097/TA.0000000000002012.

Abstract

BACKGROUND

There exists significant controversy regarding the use of suprapubic tubes (SPT) in pelvic fracture urethral injury (PFUI) patients undergoing internal fixation (IF) as to the potential risk of infection. Using the National Trauma Data Bank, we sought to examine if placement of SPT in patients with traumatic urethral injuries undergoing IF of pelvic fractures increases the risks of infectious complications during the index hospitalization.

PATIENTS AND METHODS

Using International Classification of Disease, version 9 and Abbreviated Injury Scale codes, patients with PFUI were identified in the National Trauma Data Bank between 2002 and 2014. International Classification of Disease, version 9 codes were used to identify patients who underwent IF of pelvic fractures, as well as those who underwent SPT placement. Covariates analyzed included age, Injury Severity Score (ISS), diabetes, hypertension, coronary artery disease, obesity, smoking status, associated colorectal injuries, and pelvic angioembolization. Demographics, management and infectious complications were compared between IF patients who did or did not undergo SPT placement using χ and t tests. Poisson regression analysis was performed to identify independent predictors of infectious complications.

RESULTS

Six hundred ninety-six PFUI patients were identified. Two hundred four (29.3%) patients underwent IF during the index hospitalization, of which 35 underwent concomitant SPT placement during that same admission. There was no difference in likelihood of undergoing IF in patients with or without SPT (p = 0.36). Multivariate analysis revealed that only ISS (Relative risk [RR], 4.00; 95% confidence interval, 1.25-12.77) and smoking status (RR, 2.45; 95% confidence interval, 1.11-5.43) were significant predictors of infectious complications, while SPT placement was not.

CONCLUSION

Among patients with PFUI undergoing IF, SPT placement does not appear to increase the risk for acute infectious complications during the index hospitalization, while higher ISS and smoking are significantly associated. Further longitudinal studies are required to provide definitive recommendations regarding the long-term safety of SPT placement in this patient population.

LEVEL OF EVIDENCE

Prognostic, level IV.

摘要

背景

在接受骨盆骨折内固定 (IF) 的骨盆骨折尿道损伤 (PFUI) 患者中,关于使用耻骨上管 (SPT) 是否会增加感染的潜在风险,存在很大争议。本研究利用国家创伤数据库,旨在探讨在接受骨盆骨折 IF 的创伤性尿道损伤患者中,放置 SPT 是否会增加指数住院期间感染性并发症的风险。

方法

使用国际疾病分类第 9 版 (ICD-9) 和损伤严重程度评分 (ISS) 编码,在国家创伤数据库中筛选 2002 年至 2014 年期间 PFUI 患者。使用 ICD-9 编码识别接受骨盆骨折 IF 的患者以及接受 SPT 放置的患者。分析的协变量包括年龄、ISS、糖尿病、高血压、冠心病、肥胖、吸烟状况、合并结直肠损伤和骨盆血管栓塞。使用 χ2 和 t 检验比较 IF 患者中是否放置 SPT 的患者的人口统计学、管理和感染性并发症。采用泊松回归分析确定感染性并发症的独立预测因素。

结果

共纳入 696 例 PFUI 患者。204 例(29.3%)患者在指数住院期间接受 IF,其中 35 例在同一住院期间接受了同时放置 SPT。有或没有 SPT 的患者接受 IF 的可能性没有差异(p = 0.36)。多变量分析显示,只有 ISS(相对风险 [RR],4.00;95%置信区间,1.25-12.77)和吸烟状况(RR,2.45;95%置信区间,1.11-5.43)是感染性并发症的显著预测因素,而 SPT 放置不是。

结论

在接受 IF 的 PFUI 患者中,SPT 放置似乎不会增加指数住院期间急性感染性并发症的风险,而较高的 ISS 和吸烟状况与感染性并发症显著相关。需要进一步的纵向研究来为该患者人群中 SPT 放置的长期安全性提供明确建议。

证据水平

预后,IV 级。

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