Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois.
作者信息
Ogasawara Noriko, Klingler Aiko I, Tan Bruce K, Poposki Julie A, Hulse Kathryn E, Stevens Whitney W, Peters Anju T, Grammer Leslie C, Welch Kevin C, Smith Stephanie S, Conley David B, Kern Robert C, Schleimer Robert P, Kato Atsushi
机构信息
Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
出版信息
Allergy. 2018 Nov;73(11):2251-2254. doi: 10.1111/all.13552. Epub 2018 Jul 26.
Abstract
摘要
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Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois.2型炎症的上皮激活因子：在伊利诺伊州芝加哥市患有鼻息肉的慢性鼻-鼻窦炎患者中，胸腺基质淋巴细胞生成素升高，而白细胞介素-25和白细胞介素-33未升高。
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本文引用的文献
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The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.IL-33/ST2 轴在金黄色葡萄球菌来源的丝氨酸蛋白酶样蛋白 D 诱导的 2 型气道反应中至关重要。
J Allergy Clin Immunol. 2018 Feb;141(2):549-559.e7. doi: 10.1016/j.jaci.2017.05.004. Epub 2017 May 19.
2
Alternative splicing of interleukin-33 and type 2 inflammation in asthma.白细胞介素-33的可变剪接与哮喘中的2型炎症
Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8765-70. doi: 10.1073/pnas.1601914113. Epub 2016 Jul 18.
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Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.阿司匹林加重性呼吸疾病涉及半胱氨酰白三烯驱动的白细胞介素-33介导的肥大细胞激活途径。
J Immunol. 2015 Oct 15;195(8):3537-45. doi: 10.4049/jimmunol.1500905. Epub 2015 Sep 4.
4
Cytokines in Chronic Rhinosinusitis. Role in Eosinophilia and Aspirin-exacerbated Respiratory Disease.慢性鼻-鼻窦炎中的细胞因子。在嗜酸性粒细胞增多和阿司匹林诱发的呼吸道疾病中的作用。
Am J Respir Crit Care Med. 2015 Sep 15;192(6):682-94. doi: 10.1164/rccm.201412-2278OC.
5
Immunopathology of chronic rhinosinusitis.慢性鼻-鼻窦炎的免疫病理学
Allergol Int. 2015 Apr;64(2):121-30. doi: 10.1016/j.alit.2014.12.006. Epub 2015 Feb 9.
6
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells.白细胞介素-33的中央结构域被肥大细胞蛋白酶切割，以有效激活2型固有淋巴细胞。
Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15502-7. doi: 10.1073/pnas.1410700111. Epub 2014 Oct 13.
7
IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps.IL-33 反应性固有淋巴细胞是慢性鼻息肉鼻窦炎中 IL-13 的重要来源。
Am J Respir Crit Care Med. 2013 Aug 15;188(4):432-9. doi: 10.1164/rccm.201212-2227OC.
8
Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis.胸腺基质淋巴细胞生成素活性在慢性鼻-鼻窦炎患者的鼻息肉中增加。
J Allergy Clin Immunol. 2013 Sep;132(3):593-600.e12. doi: 10.1016/j.jaci.2013.04.005. Epub 2013 May 17.
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Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps.慢性鼻息肉鼻窦炎患者白细胞介素 6 通路活性改变的证据。
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