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Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois.

作者信息

Ogasawara Noriko, Klingler Aiko I, Tan Bruce K, Poposki Julie A, Hulse Kathryn E, Stevens Whitney W, Peters Anju T, Grammer Leslie C, Welch Kevin C, Smith Stephanie S, Conley David B, Kern Robert C, Schleimer Robert P, Kato Atsushi

机构信息

Division of Allergy and Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

出版信息

Allergy. 2018 Nov;73(11):2251-2254. doi: 10.1111/all.13552. Epub 2018 Jul 26.

DOI:10.1111/all.13552
PMID:29987901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6242734/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b906/6242734/8b0e64c93292/nihms-980797-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b906/6242734/9abebbaa9140/nihms-980797-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b906/6242734/8b0e64c93292/nihms-980797-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b906/6242734/9abebbaa9140/nihms-980797-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b906/6242734/8b0e64c93292/nihms-980797-f0002.jpg

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Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois.2型炎症的上皮激活因子：在伊利诺伊州芝加哥市患有鼻息肉的慢性鼻-鼻窦炎患者中，胸腺基质淋巴细胞生成素升高，而白细胞介素-25和白细胞介素-33未升高。
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The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.IL-33/ST2 轴在金黄色葡萄球菌来源的丝氨酸蛋白酶样蛋白 D 诱导的 2 型气道反应中至关重要。
J Allergy Clin Immunol. 2018 Feb;141(2):549-559.e7. doi: 10.1016/j.jaci.2017.05.004. Epub 2017 May 19.
2
Alternative splicing of interleukin-33 and type 2 inflammation in asthma.白细胞介素-33的可变剪接与哮喘中的2型炎症
Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8765-70. doi: 10.1073/pnas.1601914113. Epub 2016 Jul 18.
3
Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.
特泽佩umab可抑制慢性鼻-鼻窦炎中高活性截短型胸腺基质淋巴细胞生成素。
J Allergy Clin Immunol. 2025 Aug;156(2):463-467.e2. doi: 10.1016/j.jaci.2025.02.031. Epub 2025 Mar 6.
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Type 2 immunity in allergic diseases.过敏性疾病中的2型免疫。
Cell Mol Immunol. 2025 Mar;22(3):211-242. doi: 10.1038/s41423-025-01261-2. Epub 2025 Feb 17.
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Nonsteroidal antiinflammatory drug-exacerbated respiratory disease: molecular mechanism, management and treatment.非甾体抗炎药加重的呼吸系统疾病：分子机制、管理与治疗
Front Allergy. 2024 Nov 27;5:1462985. doi: 10.3389/falgy.2024.1462985. eCollection 2024.
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Anti-IgE therapy in chronic rhinosinusitis with nasal polyps.抗IgE疗法用于伴鼻息肉的慢性鼻-鼻窦炎
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Curr Opin Allergy Clin Immunol. 2024 Feb 1;24(1):1-8. doi: 10.1097/ACI.0000000000000954. Epub 2023 Nov 15.
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J Immunol. 2015 Oct 15;195(8):3537-45. doi: 10.4049/jimmunol.1500905. Epub 2015 Sep 4.
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Cytokines in Chronic Rhinosinusitis. Role in Eosinophilia and Aspirin-exacerbated Respiratory Disease.慢性鼻-鼻窦炎中的细胞因子。在嗜酸性粒细胞增多和阿司匹林诱发的呼吸道疾病中的作用。
Am J Respir Crit Care Med. 2015 Sep 15;192(6):682-94. doi: 10.1164/rccm.201412-2278OC.
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Immunopathology of chronic rhinosinusitis.慢性鼻-鼻窦炎的免疫病理学
Allergol Int. 2015 Apr;64(2):121-30. doi: 10.1016/j.alit.2014.12.006. Epub 2015 Feb 9.
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Am J Respir Crit Care Med. 2013 Aug 15;188(4):432-9. doi: 10.1164/rccm.201212-2227OC.
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J Allergy Clin Immunol. 2013 Sep;132(3):593-600.e12. doi: 10.1016/j.jaci.2013.04.005. Epub 2013 May 17.
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Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps.慢性鼻息肉鼻窦炎患者白细胞介素 6 通路活性改变的证据。
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