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病例报告：肾上腺结核所致艾迪生病。

A case report: Addison disease caused by adrenal tuberculosis.

作者信息

Soedarso Moh Adi, Nugroho K Hery, Meira Dewi K A

机构信息

Division of Urology, Surgery Department, Academic Medical Center Dr. Kariadi Hospital, Faculty of Medicine, University of Diponegoro, Semarang, Indonesia.

Division of Endocrinology, Internal Medicine Department, Academic Medical Center Dr. Kariadi Hospital, Faculty of Medicine, University of Diponegoro, Semarang, Indonesia.

出版信息

Urol Case Rep. 2018 May 26;20:12-14. doi: 10.1016/j.eucr.2018.05.015. eCollection 2018 Sep.

DOI:10.1016/j.eucr.2018.05.015
PMID:29988545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6026684/
Abstract

We report middle age man with skin hyperpigmentation oral and lip mucous membranes, general malaise and depression. Further examinations lead to adrenal insufficiency, Addison's disease. Imaging studies show bilateral adrenal hyperplasia, show negative result for tuberculosis. We perform laparoscopic adrenalectomy. Multiple caseosa necrosis in gross specimen and Langhan's giant cells microscopic appearance ensure patient suffered Addison's disease cause by adrenal gland tuberculosis.

摘要

我们报告了一名中年男性，有皮肤色素沉着、口腔和唇部黏膜病变、全身不适及抑郁症状。进一步检查发现肾上腺功能不全，即艾迪生病。影像学研究显示双侧肾上腺增生，结核检查结果为阴性。我们进行了腹腔镜肾上腺切除术。大体标本中见多处干酪样坏死，镜下可见朗汉斯巨细胞，确诊患者患有由肾上腺结核引起的艾迪生病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/07daa98c571e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/4948cf4db2bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/6b77a4f9d80d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/07daa98c571e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/4948cf4db2bb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/6b77a4f9d80d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cf0/6026684/07daa98c571e/gr3.jpg

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本文引用的文献

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2
False-negative interferon-γ release assay results in active tuberculosis: a TBNET study.γ-干扰素释放试验在活动性肺结核中的假阴性结果：一项TBNET研究
Eur Respir J. 2015 Jan;45(1):279-83. doi: 10.1183/09031936.00120214. Epub 2014 Oct 30.
肾上腺脓肿：文献系统综述
J Clin Med. 2023 Jul 11;12(14):4601. doi: 10.3390/jcm12144601.
4
Complete heart block revealing adrenal tuberculosis.完全性心脏传导阻滞揭示肾上腺结核。
Radiol Case Rep. 2023 Mar 7;18(5):1856-1861. doi: 10.1016/j.radcr.2023.01.096. eCollection 2023 May.
5
New Approach to Addison Disease: Oral Manifestations Due to Endocrine Dysfunction and Comorbidity Burden.艾迪生病的新研究方向：内分泌功能障碍及合并症负担导致的口腔表现
Diagnostics (Basel). 2022 Aug 28;12(9):2080. doi: 10.3390/diagnostics12092080.
6
Primary adrenal tuberculosis infection in patients with Behcet's disease presenting as isolated adrenal metastasis by F-FDG PET/CT: a rare case report and literature review.白塞病患者原发性肾上腺结核感染表现为F-FDG PET/CT显示的孤立性肾上腺转移：1例罕见病例报告及文献复习
Gland Surg. 2021 Dec;10(12):3431-3442. doi: 10.21037/gs-21-511.
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Bilateral adrenal masses due to tuberculosis: how to diagnose without extra-adrenal tuberculosis.双侧肾上腺结核肿块：如何在无肾上腺外结核的情况下进行诊断。
Endocrinol Diabetes Metab Case Rep. 2021 Dec 1;2021. doi: 10.1530/EDM-21-0093.
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Unusual case of antiphospholipid syndrome presenting as adrenal insufficiency.表现为肾上腺功能不全的抗磷脂综合征罕见病例。
BMJ Case Rep. 2020 Mar 17;13(3):e233631. doi: 10.1136/bcr-2019-233631.