Lithium suppresses hibernation in the Turkish hamster.

Daily uptake of lithium salt (LiCl) in the drinking water at a rate of over 100 micrograms/g b.wt (or 2.4 mEq/kg) reduced or suppressed natural torpidity (hibernation) in the Turkish hamster (Mesocricetus brandti). The data indicate a direct influence of lithium on clock-related functions controlling the hibernation process rather than indirect effects by preventing gonadal regression and thereby also hibernation.