Lantz I, Terenius L
FEBS Lett. 1985 Nov 25;193(1):31-4. doi: 10.1016/0014-5793(85)80073-9.
The metabolism of enkephalin peptides was studied in human cerebrospinal fluid. The degradation rates of (Leu)-enkephalin and (Leu)-enkephalin-Arg6 were compared and the latter was degraded at a 10-fold higher rate. The major enzyme activity was investigated by Mr determination and inhibition experiments, showing marked similarity with angiotensin-converting enzyme.
在人类脑脊液中研究了脑啡肽的代谢。比较了亮氨酸脑啡肽和亮氨酸脑啡肽-精氨酸6的降解速率，发现后者的降解速率要高10倍。通过分子量测定和抑制实验研究了主要的酶活性，结果显示其与血管紧张素转换酶具有显著相似性。
