Mechanisms of sarcopenia: motor unit remodelling and muscle fibre type shifts with ageing.
作者信息
Machek Steven Brian
机构信息
Muscle Physiology Laboratory, San Francisco State University, San Francisco, California, USA.
出版信息
J Physiol. 2018 Aug;596(16):3467-3468. doi: 10.1113/JP276586. Epub 2018 Jul 23.
Abstract
摘要
相似文献
1
Mechanisms of sarcopenia: motor unit remodelling and muscle fibre type shifts with ageing.肌肉减少症的机制：运动单位重塑与衰老过程中的肌纤维类型转变
J Physiol. 2018 Aug;596(16):3467-3468. doi: 10.1113/JP276586. Epub 2018 Jul 23.
2
Age-dependent motor unit remodelling in human limb muscles.人类肢体肌肉中与年龄相关的运动单位重塑
Biogerontology. 2016 Jun;17(3):485-96. doi: 10.1007/s10522-015-9627-3. Epub 2015 Dec 14.
3
Effect of ageing on the myosin heavy chain composition of the human sternocleidomastoid muscle.衰老对人胸锁乳突肌肌球蛋白重链组成的影响。
Ann Anat. 2018 Mar;216:95-99. doi: 10.1016/j.aanat.2017.12.001. Epub 2017 Dec 28.
4
Absence of morphological and molecular correlates of sarcopenia in the macaque tongue muscle styloglossus.猕猴舌肌茎突舌肌中无肌肉减少症的形态学和分子学相关因素。
Exp Gerontol. 2016 Nov;84:40-48. doi: 10.1016/j.exger.2016.08.010. Epub 2016 Aug 24.
5
Motor unit loss is accompanied by decreased peak muscle power in the lower limb of older adults.运动单位丧失伴随着老年人下肢肌肉峰值功率的降低。
Exp Gerontol. 2015 Oct;70:111-8. doi: 10.1016/j.exger.2015.07.007. Epub 2015 Jul 17.
6
Skeletal Muscle Regeneration, Repair and Remodelling in Aging: The Importance of Muscle Stem Cells and Vascularization.衰老过程中的骨骼肌再生、修复与重塑：肌肉干细胞和血管生成的重要性
Gerontology. 2017;63(1):91-100. doi: 10.1159/000450922. Epub 2016 Oct 20.
7
Drastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old age.衰老骨骼肌中肌球蛋白轻链MLC-2的急剧增加表明老年肌肉减少症中快肌纤维向慢肌纤维的转变。
Eur J Cell Biol. 2009 Nov;88(11):685-700. doi: 10.1016/j.ejcb.2009.06.004. Epub 2009 Jul 19.
8
Physical inactivity is a major contributor to ovariectomy-induced sarcopenia.缺乏身体活动是去卵巢诱导性肌肉减少症的一个主要原因。
Int J Sports Med. 2012 Apr;33(4):268-78. doi: 10.1055/s-0031-1297953. Epub 2012 Jan 19.
9
Effects of aging on muscle fibre type and size.衰老对肌纤维类型和大小的影响。
Sports Med. 2004;34(12):809-24. doi: 10.2165/00007256-200434120-00002.
10
Age-related loss of muscle fibres is highly variable amongst mouse skeletal muscles.衰老导致的肌肉纤维损失在小鼠骨骼肌中具有高度可变性。
Biogerontology. 2012 Apr;13(2):157-67. doi: 10.1007/s10522-011-9365-0. Epub 2011 Nov 3.
引用本文的文献
1
Advancing muscle aging and sarcopenia research through spatial transcriptomics.通过空间转录组学推进肌肉衰老和肌肉减少症研究。
Osteoporos Sarcopenia. 2025 Jun;11(2 Suppl):22-31. doi: 10.1016/j.afos.2025.05.002. Epub 2025 Jun 12.
2
The Current Landscape of Pharmacotherapies for Sarcopenia.肌少症药物治疗的现状。
Drugs Aging. 2024 Feb;41(2):83-112. doi: 10.1007/s40266-023-01093-7. Epub 2024 Feb 5.
3
Understanding the Consequences of Fatty Bone and Fatty Muscle: How the Osteosarcopenic Adiposity Phenotype Uncovers the Deterioration of Body Composition.了解脂肪骨和脂肪肌肉的后果：骨肌减少性肥胖表型如何揭示身体成分的恶化。
Metabolites. 2023 Oct 7;13(10):1056. doi: 10.3390/metabo13101056.
4
Sarcopenia parameters in active older adults - an eight-year longitudinal study.活跃老年人的肌肉减少症参数-一项八年纵向研究。
BMC Public Health. 2023 May 19;23(1):917. doi: 10.1186/s12889-023-15734-4.
5
Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD).非酒精性脂肪性肝病 (NAFLD) 中生活方式干预的病理生理学。
Nutrients. 2020 Nov 12;12(11):3472. doi: 10.3390/nu12113472.
6
Semiautomatic morphometric analysis of skeletal muscle obtained by needle biopsy in older adults.老年人经皮骨骼肌活检获得的骨骼肌半自动形态计量分析。
Geroscience. 2020 Dec;42(6):1431-1443. doi: 10.1007/s11357-020-00266-1. Epub 2020 Sep 18.
本文引用的文献
1
Failure to expand the motor unit size to compensate for declining motor unit numbers distinguishes sarcopenic from non-sarcopenic older men.未能扩大运动单位大小以补偿运动单位数量的下降，将肌少症与非肌少症的老年男性区分开来。
J Physiol. 2018 May 1;596(9):1627-1637. doi: 10.1113/JP275520. Epub 2018 Mar 23.
2
Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians.去神经支配导致八旬老人骨骼肌中的线粒体功能障碍。
J Physiol. 2016 Dec 15;594(24):7361-7379. doi: 10.1113/JP272487. Epub 2016 Oct 23.
3
Improved single muscle fiber quality in the oldest-old.最年长者的单肌纤维质量得到改善。
J Appl Physiol (1985). 2016 Oct 1;121(4):878-884. doi: 10.1152/japplphysiol.00479.2016. Epub 2016 Aug 11.
4
Improving human skeletal muscle myosin heavy chain fiber typing efficiency.提高人类骨骼肌肌球蛋白重链纤维分型效率。
J Muscle Res Cell Motil. 2016 Apr;37(1-2):1-5. doi: 10.1007/s10974-016-9441-9. Epub 2016 Feb 3.
5
Innervation and neuromuscular control in ageing skeletal muscle.衰老骨骼肌中的神经支配与神经肌肉控制
J Physiol. 2016 Apr 15;594(8):1965-78. doi: 10.1113/JP270561. Epub 2015 Dec 21.
6
Muscle strength, power and adaptations to resistance training in older people.老年人的肌肉力量、功率及对阻力训练的适应性
Eur J Appl Physiol. 2004 Apr;91(4):450-72. doi: 10.1007/s00421-003-0991-3. Epub 2003 Nov 25.
7
Increase in the degree of coexpression of myosin heavy chain isoforms in skeletal muscle fibers of the very old.
Muscle Nerve. 1999 Apr;22(4):449-54. doi: 10.1002/(sici)1097-4598(199904)22:4<449::aid-mus4>3.0.co;2-2.
Zotero 插件