Santos A D, Benchimol A, Desser K B, Graves C
J Thorac Cardiovasc Surg. 1977 Feb;73(2):231-6.
Pre- and postoperative hemodynamic indices were compared in 116 patients subjected to aorto-coronary bypass after an average interval of 128 days. The patients were separated into three different groups according to graft status: Group 1 (n = 77), all grafts patent; Group 2 (n = 27), one occluded graft out of two or three implanted; Group 3 (n = 12), all grafts occluded. There were no significant major changes of values so obtained in the three groups. Those subjects with initially depressed cardiac indices or elevated left ventricular end-diastolic pressures manifested a significant trend toward improvement when at least one bypass graft was patent. A reduction of cardiac index was noted in patients with occluded left anterior descending coronary grafts only in association with closure of other grafts. Deterioration of cardiac index or left ventricular end-diastolic pressure into the abnormal range was unusual in the study group, even when all grafts were occluded. It is concluded that data relating to the influence of aorto-coronary bypass on standard indices of left ventricular function can be properly interpreted only when certain subsets of patients are studied.
在平均间隔128天后，对116例行主动脉冠状动脉搭桥术的患者术前和术后的血流动力学指标进行了比较。根据移植血管状态，将患者分为三组：第1组（n = 77），所有移植血管通畅；第2组（n = 27），植入的两根或三根移植血管中有一根闭塞；第3组（n = 12），所有移植血管均闭塞。三组中如此获得的值没有显著的主要变化。那些最初心脏指数降低或左心室舒张末期压力升高的受试者，当至少有一根搭桥血管通畅时，表现出显著的改善趋势。仅在其他移植血管闭塞的情况下，左前降支冠状动脉移植血管闭塞的患者才出现心脏指数降低。在研究组中，即使所有移植血管均闭塞，心脏指数或左心室舒张末期压力恶化至异常范围的情况也不常见。结论是，只有对特定亚组的患者进行研究，才能正确解释主动脉冠状动脉搭桥术对左心室功能标准指标影响的数据。
