a Department of Ophthalmology, Eye and ENT Hospital of Fudan University , Shanghai, P. R . China.
b Shanghai Key Laboratory of Visual Impairment and Restoration, Fudan University , Shanghai, P. R . China.
Ocul Immunol Inflamm. 2019;27(5):747-755. doi: 10.1080/09273948.2018.1465100. Epub 2018 Jul 11.
: To summarize the characteristics of endogenous fungal endophthalmitis (EFE) after genitourinary procedures. : Medical records of patients diagnosed with EFE after genitourinary procedures from a single center during a 6-year period were reviewed. : Nineteen eyes of 15 patients were included. The interval time between procedure to symptom was 3.6 ± 3.6 weeks. As the initial treatment, 9/19 eyes underwent primary vitrectomy and 10/19 eyes underwent intravitreal antifungal injection . was the pathogen in 15 of 19 eyes. Systemic treatment with itraconazole was used in all patients. LogMAR best corrected visual acuity improved from 2.2 ± 0.9 to 0.9 ± 1.2 after treatment ( = 0.002) in 15 eyes that were followed-up for an average of 4.9 ± 2.1 years. : Genitourinary procedure is a predisposing factor for EFE. is the predominant pathogen. Normative systemic and local antifungal treatments improved the final visual outcome.
总结泌尿生殖系统操作后内源性真菌性眼内炎（EFE）的特点。
回顾单中心 6 年间泌尿生殖系统操作后诊断为 EFE 的患者的病历。
纳入 15 例患者的 19 只眼。症状出现到操作的间隔时间为 3.6±3.6 周。作为初始治疗，9/19 只眼接受了玻璃体切除术，10/19 只眼接受了眼内抗真菌注射。19 只眼中的 15 只有病原体。所有患者均接受了伊曲康唑全身治疗。在平均随访 4.9±2.1 年后，15 只眼的 LogMAR 最佳矫正视力从 2.2±0.9 提高到 0.9±1.2（=0.002）。
泌尿生殖系统操作是 EFE 的诱发因素。念珠菌是主要病原体。规范的全身和局部抗真菌治疗改善了最终的视力结局。
