IEEE Trans Med Imaging. 2018 Sep;37(9):2080-2089. doi: 10.1109/TMI.2018.2816125. Epub 2018 May 18.
Contrast source inversion-electrical properties tomography (CSI-EPT) is an iterative reconstruction method to retrieve the electrical properties (EPs) of tissues from magnetic resonance data. The method is based on integral representations of the electromagnetic field and has been shown to allow EP reconstructions of small structures as well as tissue boundaries with compelling accuracy. However, to date, the CSI-EPT has been implemented for 2-D configurations only, which limits its applicability. In this paper, a full 3-D extension of the CSI-EPT method is presented, to enable CSI-EPT to be applied to realistic 3-D scenarios. Here, we demonstrate a proof-of-principle of 3-D CSI-EPT and present the reconstructions of a 3-D abdominal body section and a 3-D head model using different settings of the transmit coil. Numerical results show that the full 3-D approach yields accurate reconstructions of the EPs, even at tissue boundaries and is most accurate in regions where the absolute value of the electric field is highest.
对比源反演-电学特性层析成像（CSI-EPT）是一种从磁共振数据中获取组织电学特性（EP）的迭代重建方法。该方法基于电磁场的积分表示，已被证明可以对小结构以及具有令人信服准确性的组织边界进行 EP 重建。然而，迄今为止，CSI-EPT 仅在 2D 配置中实现，这限制了其适用性。本文提出了 CSI-EPT 方法的全 3D 扩展，以使 CSI-EPT 能够应用于现实的 3D 场景。在这里，我们演示了 3D CSI-EPT 的原理验证，并展示了使用不同发射线圈设置对 3D 腹部体段和 3D 头部模型的重建。数值结果表明，全 3D 方法即使在组织边界处也能准确重建 EP，并且在电场绝对值最高的区域最为准确。
