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儿童面部外受累的肉芽肿性口周皮炎:口服阿奇霉素治疗反应良好

GRANULOMATOUS PERIORAL DERMATITIS WITH EXTRA-FACIAL INVOLVEMENT IN CHILDHOOD: GOOD THERAPEUTIC RESPONSE WITH ORAL AZITHROMYCIN.

作者信息

Milagre Ana Carolina Xavier, Almeida Ana Paula Moura de, Rezende Hudson Dutra, Almeida Liana Moura de, Peçanha Maria Auxiliadora Peixoto

机构信息

Hospital Escola Álvaro Alvim, Campos dos Goytacazes, RJ, Brasil.

出版信息

Rev Paul Pediatr. 2018 Oct-Dec;36(4):511-514. doi: 10.1590/1984-0462/;2018;36;4;00004. Epub 2018 Jul 10.

Abstract

OBJECTIVE

To present a case of granulomatous perioral dermatitis (GPD) with extra-facial involvement and good response to short-term treatment with oral macrolide.

CASE DESCRIPTION

A 9-year-old girl presented with exuberant GPD with extra-facial involvement. During follow-up, she received multiple ineffective therapies, but showed significant improvement of the lesions after the use of azithromycin for five days.

COMMENTS

GPD is an inflammatory dermatological condition represented by papulo-erythematous eruptions on perioral, nasal and periorbital regions, more prevalent in children and adolescents. It rarely extends to the genital region, trunk, and extremities, which characterizes its extra-facial manifestation. Its etiology is unknown, but it seems to have a correlation with the use of topical corticosteroids and other agents.

摘要

目的

报告1例肉芽肿性口周皮炎(GPD)累及面部以外部位且对口服大环内酯类药物短期治疗反应良好的病例。

病例描述

一名9岁女孩出现累及面部以外部位的重度GPD。在随访期间,她接受了多种无效治疗,但在使用阿奇霉素5天后皮损有显著改善。

评论

GPD是一种炎症性皮肤病,表现为口周、鼻周和眶周的丘疹性红斑疹,在儿童和青少年中更为常见。它很少扩展到生殖器区域、躯干和四肢,这是其面部以外表现的特征。其病因不明,但似乎与外用糖皮质激素及其他药物的使用有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc04/6322805/d7c0f5d2cf27/0103-0582-rpp-2018-36-4-00004-gf1.jpg

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