Kobetz Erin, Seay Julia, Koru-Sengul Tulay, Bispo Jordan Baeker, Trevil Dinah, Gonzalez Martha, Brickman Andrew, Carrasquillo Olveen
Department of Medicine, University of Miami Miller School of Medicine, Miami-Dade, FL, USA.
Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami-Dade, FL, USA.
Cancer Causes Control. 2018 Sep;29(9):793-801. doi: 10.1007/s10552-018-1055-7. Epub 2018 Jul 11.
HPV self-sampling has previously been shown to increase cervical cancer screening among ethnic minority and immigrant women. We conducted a randomized pragmatic trial to examine the effectiveness of HPV self-sampling delivered via in-person versus by US mail for medically underserved Hispanic, Haitian, and non-Hispanic Black women living in South Florida.
We randomized women aged 30-65 who had not completed Pap smear screening in the past 3 years into two groups: (1) HPV self-sampling delivered in-person (IP) by a community health worker (CHW; IP + SS) or (2) HPV self-sampling delivered via US mail (SS + Mail). Our primary outcome was HPV self-sampling completion by 6-month post-study enrollment.
We enrolled 600 women. Approximately 65% were Hispanic and 35% were Haitian or non-Hispanic Black. Nearly half (43%) had an income of less than $20,000/year and 67% were uninsured. In intent-to-treat analyses, 71.6% of participants in the SS + Mail group and 81.0% of participants in the IP + SS group completed HPV self-sampling.
Mailed HPV self-sampling is an effective strategy to increase cervical cancer screening among underserved immigrant and ethnic minority women.
人乳头瘤病毒（HPV）自我采样此前已被证明可提高少数族裔和移民妇女的宫颈癌筛查率。我们进行了一项随机实用试验，以检验通过社区卫生工作者当面提供HPV自我采样与通过美国邮政邮寄提供HPV自我采样，对居住在南佛罗里达州医疗服务不足的西班牙裔、海地裔和非西班牙裔黑人妇女的有效性。
我们将过去3年未完成巴氏涂片筛查的30 - 65岁女性随机分为两组：（1）由社区卫生工作者当面提供HPV自我采样（IP + SS），或（2）通过美国邮政邮寄提供HPV自我采样（SS + 邮件）。我们的主要结局是研究入组后6个月内完成HPV自我采样。
我们招募了600名女性。约65%为西班牙裔，35%为海地裔或非西班牙裔黑人。近一半（43%）年收入低于20,000美元，67%未参保。在意向性分析中，SS + 邮件组71.6%的参与者和IP + SS组81.0%的参与者完成了HPV自我采样。
邮寄HPV自我采样是提高医疗服务不足的移民和少数族裔妇女宫颈癌筛查率的有效策略。
