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母亲研究中的妊娠意愿与阿片类药物使用障碍治疗保留率

Pregnancy intention and opioid use disorder treatment retention in the MOTHER study.

作者信息

Martin Caitlin E, Terplan Mishka, O'Grady Kevin E, Jones Hendrée E

机构信息

University of North Carolina (UNC) Hospitals, Chapel Hill, North Carolina.

Virginia Commonwealth University Medical System, Richmond, Virginia.

出版信息

Am J Addict. 2018 Jul 11. doi: 10.1111/ajad.12735.

DOI:10.1111/ajad.12735
PMID:29995313
Abstract

BACKGROUND AND OBJECTIVES

Opioid use disorder (OUD) during pregnancy challenges public health. This study examines how pregnancy intention affects OUD treatment.

METHODS

The primary exposure and outcome were pregnancy intention and treatment duration among MOTHER (Maternal Opioid Treatment: Human Experimental Research) participants (N = 175).

RESULTS

Treatment durations were longer (21.3 vs. 16.3 weeks; p = .01) among intended (n = 29) compared to unintended (n = 146) pregnancy participants, but this was not significant in adjusted analyses.

DISCUSSION AND CONCLUSIONS

Unintended pregnancies intersect with OUD and may modify one's treatment outcomes.

SCIENTIFIC SIGNIFICANCE

OUD treatment may be a setting to help women implement informed family planning choices. (Am J Addict 2018;XX:1-3).

摘要

背景与目的

孕期阿片类物质使用障碍(OUD)对公共卫生构成挑战。本研究探讨妊娠意愿如何影响OUD治疗。

方法

主要暴露因素和结局分别为MOTHER(母亲阿片类物质治疗:人体实验研究)参与者(N = 175)的妊娠意愿和治疗持续时间。

结果

有妊娠意愿的参与者(n = 29)的治疗持续时间长于无妊娠意愿的参与者(n = 146)(21.3周对16.3周;p = .01),但在调整分析中这一差异不显著。

讨论与结论

意外怀孕与OUD相关,可能会改变治疗结果。

科学意义

OUD治疗可能是帮助女性做出明智的计划生育选择的一个契机。(《美国成瘾杂志》2018年;XX:1 - 3)

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