Chandra R, Singh I P, Garg S K
Microbiol Immunol. 1985;29(8):701-7. doi: 10.1111/j.1348-0421.1985.tb00874.x.
The buffalo pox virus was found to multiply in the skin, the primary site of inoculation with an eclipse phase of 12 hr. The virus was then detected in the skin after 15 hr followed by its appearance in regional lymph nodes 36 hr postinoculation. Primary viremia was detected 48 hr postinoculation, followed by detection of virus in the lungs, liver, and spleen. The virus multiplied in the lungs on day 4 and in the liver and spleen on day 5 postinoculation and its release led to secondary viremia. In a follow-up from day 7 to 14 postinoculation, the virus was detected in the kidneys, stomach, intestines, and gonads.
发现水牛痘病毒在皮肤中增殖，皮肤是接种的主要部位，其隐蔽期为12小时。接种15小时后在皮肤中检测到该病毒，随后在接种后36小时出现在局部淋巴结中。接种后48小时检测到原发性病毒血症，随后在肺、肝和脾中检测到病毒。接种后第4天病毒在肺中增殖，第5天在肝和脾中增殖，其释放导致继发性病毒血症。在接种后第7天至第14天的随访中，在肾、胃、肠和性腺中检测到该病毒。
