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重新审视膝关节轻度或无骨关节炎退行性撕裂行关节镜下部分半月板切除术:随机对照试验的系统评价和荟萃分析。

Revisiting Arthroscopic Partial Meniscectomy for Degenerative Tears in Knees With Mild or No Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

机构信息

Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea.

出版信息

Clin J Sport Med. 2020 May;30(3):195-202. doi: 10.1097/JSM.0000000000000585.

Abstract

OBJECTIVE

The purpose of this systematic review and meta-analysis was to evaluate the efficacy of arthroscopic partial meniscectomy (APM) for symptomatic degenerative meniscal tear (DMT) in knees with mild or no osteoarthritis.

STUDY DESIGN

A systematic review and meta-analysis.

METHODS

MEDLINE, EMBASE, and Cochrane databases were systematically searched. The inclusion criteria were as follows: (1) English language; (2) randomized controlled trial (RCT); (3) comparison between APM and other treatment modalities as a primary objective; and (4) complete DMT in knees with mild or no osteoarthritis. Mild or no arthritis was defined as Kellgren-Lawrence grade 0 to 2 or Ahlbäck 0 to 1 on radiography. Statistical analysis of functional activity and pain after APM and conservative treatment or sham operation was performed using R version 3.3.1.

RESULTS

Five articles were included in the final analysis, and they were all RCTs. Four studies compared clinical results of APM with those for physical therapy, and one study compared APM with sham operation. The functional activity was not better in the APM group (296 cases) than in the conservative treatment or sham operation group (284 cases) (I: 0%, small level of heterogeneity). Pain was not reduced significantly in the APM group compared with that in the conservative treatment or sham operation group (I: 0∼90%, high level of heterogeneity).

CONCLUSIONS

This systematic review and meta-analysis of high-quality literature provides relatively strong evidence that APM did not improve functional activity or reduce pain compared with the results with conservative treatment or sham operation in knees with mild or no osteoarthritis.

摘要

目的

本系统评价和荟萃分析的目的是评估关节镜下半月板部分切除术(APM)治疗轻度或无骨关节炎膝关节症状性退行性半月板撕裂(DMT)的疗效。

研究设计

系统评价和荟萃分析。

方法

系统检索 MEDLINE、EMBASE 和 Cochrane 数据库。纳入标准如下:(1)英语语言;(2)随机对照试验(RCT);(3)以 APM 与其他治疗方式的比较作为主要目标;(4)在轻度或无骨关节炎的膝关节中存在完全性 DMT。轻度或无关节炎定义为 X 线片上的 Kellgren-Lawrence 分级 0 至 2 级或 Ahlbäck 0 至 1 级。使用 R 版本 3.3.1 对 APM 和保守治疗或假手术治疗后的功能活动和疼痛进行统计分析。

结果

最终分析纳入了 5 篇文章,均为 RCT。4 项研究比较了 APM 的临床结果与物理治疗的结果,1 项研究比较了 APM 与假手术的结果。APM 组(296 例)的功能活动并不优于保守治疗或假手术组(284 例)(I:0%,低度异质性)。与保守治疗或假手术组相比,APM 组的疼痛并未显著减轻(I:0∼90%,高度异质性)。

结论

本项高质量文献的系统评价和荟萃分析提供了相对较强的证据,表明在轻度或无骨关节炎的膝关节中,APM 并未改善功能活动或减轻疼痛,与保守治疗或假手术的结果相比无明显优势。

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